Evidence map›Paper›PMID 16204196›Full record

ArticleGenome research2005

Differential methylation of genes and repeats in land plants.

Pablo D Rabinowicz, Robert Citek, Muhammad A Budiman, Andrew Nunberg, Joseph A Bedell, Nathan Lakey, Andrew L O'Shaughnessy, Lidia U Nascimento, W Richard McCombie, Robert A Martienssen

Open access · bronzeAbstract read
In one paragraph

Article in Genome research, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 143 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Epigenetic Variability Among Saffron Crocus (Frontiers in plant science · 2021
    Article
  7. Article
  8. Article
  9. Putting DNA methylation in context: from genomes to gene expression in plants.Biochimica et biophysica acta. Gene regulatory mechanisms · 2017
    Review
  10. An Exploration into Fern Genome Space.Genome biology and evolution · 2015
    Article
  11. Article
  12. Article
  13. Article
  14. How to Isolate a Plant's Hypomethylome in One Shot.BioMed research international · 2015
    Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Pablo D RabinowiczThe Institute for Genomic Research, Rockville, Maryland 20850, USA.
Robert Citek
Muhammad A Budiman
Andrew Nunberg
Joseph A Bedell
Nathan Lakey
Andrew L O'Shaughnessy
Lidia U Nascimento
W Richard McCombie
Robert A Martienssen
Orion Genomics (United States) · USCold Spring Harbor Laboratory · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hypomethylated fraction of plant genomes is usually enriched in genes and can be selectively cloned using methylation filtration (MF). Therefore, MF has been used as a gene enrichment technology in sorghum and maize, where gene enrichment was proportional to genome size. Here we apply MF to a broad variety of plant species spanning a wide range of genome sizes. Differential methylation of genic and non-genic sequences was observed in all species tested, from non-vascular to vascular plants, but in some cases, such as wheat and pine, a lower than expected level of enrichment was observed. Remarkably, hexaploid wheat and pine show a dramatically large number of gene-like sequences relative to other plants. In hexaploid wheat, this apparent excess of genes may reflect an abundance of methylated pseudogenes, which may thus be more prevalent in recent polyploids.

Indexed as

DNA MethylationGenes, PlantRepetitive Sequences, Nucleic AcidGene DuplicationMolecular Sequence DataPhylogenyPolyploidy

Identifiers

PMID16204196
PMCPMC1240086
OpenAlexW2086894395

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.