Evidence map›Paper›PMID 16202883›Full record

ArticleBiosensors & bioelectronics2005

Detection of water-borne E. coli O157 using the integrating waveguide biosensor.

Peixuan Zhu, Daniel R Shelton, Jeffrey S Karns, Appavu Sundaram, Shuhong Li, Pete Amstutz, Cha-Mei Tang

Open access · greenAbstract readEvaluation Study
In one paragraph

Article in Biosensors & bioelectronics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 67 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Peixuan ZhuCreatv MicroTech, Inc., 11609 Lake Potomac Drive, Potomac, MD 20854, USA. pzhu@creatvmicrotech.com
Daniel R Shelton
Jeffrey S Karns
Appavu Sundaram
Shuhong Li
Pete Amstutz
Cha-Mei Tang
Creatv MicroTech (United States) · USAgricultural Research Service · USUnited States Department of Agriculture · US

Funding

Rapid Detection of Major Food-borne PathogensR43AI052684 · NIAID · CREATV MICROTECH, INC. · PI ZHU, PEIXUAN · 2003 to 2003
$212k
NIAID NIH HHS R43 AI052684NIAID NIH HHS R43 AI152684
6 · The paper itself

Abstract

Escherichia coli O157:H7, the most common serotype of enterohemorrhagic E. coli (EHEC), is responsible for numerous food-borne and water-borne infections worldwide. An integrating waveguide biosensor is described for the detection of water-borne E. coli O157, based on a fluorescent sandwich immunoassay performed inside a glass capillary waveguide. The genomic DNA of captured E. coli O157 cells was extracted and quantitative real-time PCR subsequently performed to assess biosensor-capture efficiency. In vitro microbial growth in capillary waveguide is also documented. The biosensor allows for quantitative detection of as few as 10 cells per capillary (0.075 ml volume) and can be used in conjunction with cell amplification, PCR and microarray technologies to positively identify a pathogen.

Indexed as

Biosensing TechniquesColony Count, MicrobialEquipment DesignEquipment Failure AnalysisEscherichia coli O157ImmunoassayReverse Transcriptase Polymerase Chain ReactionSpectrometry, FluorescenceSystems Integration

Identifiers

PMID16202883
PMCPMC2483406
OpenAlexW2012693011

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.