Evidence map›Paper›PMID 16202226›Full record

ArticleJournal of cellular and molecular medicine

Cajal-type cells from human mammary gland stroma: phenotype characteristics in cell culture.

E Radu, T Regalia, Laura Ceafalan, F Andrei, D Cretoiu, L M Popescu

Open access · greenAbstract read
In one paragraph

Article in Journal of cellular and molecular medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Telocytes and interstitial cells of Cajal in the biliary system.Journal of cellular and molecular medicine · 2018
    Review
  3. Article
  4. Calcium Signaling in Interstitial Cells: Focus on Telocytes.International journal of molecular sciences · 2017
    Review
  5. Article
  6. Telocytes in trachea and lungs.Journal of cellular and molecular medicine · 2011
    Article
  7. Article
  8. Review
  9. Article
  10. Ethical issues in cellular and molecular medicine and tissue engineering.Journal of cellular and molecular medicine · 2008
    Article
  11. Interstitial Cajal-like cells in human gallbladder.Journal of molecular histology · 2007
    Article
  12. Article
  13. Future perspectives in tissue engineering.Journal of cellular and molecular medicine
    Article
  14. Article
  15. Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

E RaduDepartment of Cellular and Molecular Medicine, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
T Regalia
Laura Ceafalan
F Andrei
D Cretoiu
L M Popescu
Carol Davila University of Medicine and Pharmacy · ROInstitutul National Victor Babes · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report here the in vitro isolation of Cajal-like interstitial cells from human inactive mammary-gland stroma. Primary cell cultures examined in phase-contrast microscopy or after vital methylene-blue staining revealed a cell population with characteristic morphological phenotype: fusiform, triangular or polygonal cell body and the corresponding (very) long, slender, moniliform cytoplasmic processes. Giemsa staining pointed out the typical knobbed aspect of cell prolongations. Immunofluorescence (IF) showed, like in situ immunohistochemistry, that Cajal-type cells in vitro (primary cultures), expressed c-kit/CD117 and vimentin. In conclusion, the images presented here reinforce our previous hypothesis that human mammary glands have a distinct population of Cajal-like cells in non-epithelial tissue compartments.

Indexed as

BreastCell Culture TechniquesFemaleHumansMicroscopy, FluorescenceMicroscopy, Phase-ContrastStromal Cells

Identifiers

PMID16202226
PMCPMC6741633
OpenAlexW2061305669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.