ArticleJournal of molecular histology2005
Expression of versican and ADAMTS during rat tooth eruption.
Article in Journal of molecular histology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 39 citations in OpenAlex.
- Gene expression and immunohistochemistry analysis of ADAMTS-1 and its substrates in odontogenic keratocyst.Diagnostic pathology · 2025Article
- Gene Expression and Immunochemistry Analysis of ADAMTS-1 and Versican in Ameloblastoma.International journal of dentistry · 2022Article
- Immunohistochemical analysis of ADAMTS-1, versican and pEGFR expressions in periapical granuloma and radicular cyst.BMC oral health · 2021Article
- Versican contributes to ligament formation of knee joints.PloS one · 2021Article
- Homozygous Recessive Versican Missense Variation Is Associated With Early Teeth Loss in a Pakistani Family.Frontiers in genetics · 2018Article
- Comparison of gene expression profiles between dental pulp and periodontal ligament tissues in humans.International journal of molecular medicine · 2017Article
- Genomic occupancy of Runx2 with global expression profiling identifies a novel dimension to control of osteoblastogenesis.Genome biology · 2014Article
- Comparative gene expression analysis of the human periodontal ligament in deciduous and permanent teeth.PloS one · 2013Article
- Developmental changes and regional localization of Dspp, Mepe, Mimecan and Versican in postnatal developing mouse teeth.Journal of molecular histology · 2012Article
- A Large Chondroitin Sulfate Proteoglycan, Versican, in Porcine Predentin.Journal of oral biosciences · 2011Article
- Synthesis and organization of hyaluronan and versican by embryonic stem cells undergoing embryoid body differentiation.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2010Article
- Immunohistochemical and biochemical assay of versican in human sound predentine/dentine matrix.European journal of histochemistry : EJH · 2009Review
- Immunolocalization of proteoglycans in Meckel's cartilage of the rat.The open dentistry journal · 2009Article
- Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-beta/bone morphogenic protein signalling.Arthritis research & therapy · 2007Article
- The MMP activity in developing rat molar roots and incisors demonstrated by in situ zymography.Journal of molecular histology · 2006Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A disintegrin and metalloprotease with thrombospondin type 1 motifs (ADAMTS) is a family of extracellular proteases and implicated in cleaving proteoglycans, such as aggrecan, versican and brevican. No information is available about expression or localization of these ADAMTSs in teeth. Versican is a large chondroitin sulfate proteoglycan that is present in a variety of connective tissue including dental pulp, dentin, cementum and periodontal ligaments. The present study was designed to investigate expression of ADAMTSs and versican during rat tooth eruption. Rat maxillary first molars in weeks 1, 2, 3, 4 and 6 were examined. The mRNA expression of ADAMTS1, ADAMTS4, ADAMTS5 and versican was localized using in situ hybridization. ADAMTS1, ADAMTS4, ADAMTS5 and versican were expressed in dental pulp cells, odontoblasts, cementoblasts, cementocytes, periodontal ligament cells, osteoblasts and osteocytes. The temporal and spatial expression pattern in these cellular phenotypes was comparable among ADAMTSs and versican. The present study suggests that dental pulp cells, odontoblasts, cementoblasts, cementocytes, periodontal ligament cells, osteoblasts and osteocytes may be involved in both production and degradation of versican with secreting ADAMTS1, ADAMTS4 and ADAMTS5.
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