ArticleRNA (New York, N.Y.)2005
Association of ribosomal proteins with nascent transcripts in S. cerevisiae.
Article in RNA (New York, N.Y.), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 21 citations in OpenAlex.
- Article
- Localization and Functional Roles of Components of the Translation Apparatus in the Eukaryotic Cell Nucleus.Cells · 2021Review
- Ribosomal Proteins Rpl22 and Rpl22l1 Control Morphogenesis by Regulating Pre-mRNA Splicing.Cell reports · 2017Article
- Cap-binding complex (CBC).The Biochemical journal · 2014Review
- Visualization of the joining of ribosomal subunits reveals the presence of 80S ribosomes in the nucleus.RNA (New York, N.Y.) · 2013Article
- New partners in regulation of gene expression: the enhancer of Trithorax and Polycomb Corto interacts with methylated ribosomal protein l12 via its chromodomain.PLoS genetics · 2012Article
- Ribosomal proteins' association with transcription sites peaks at tRNA genes in Schizosaccharomyces pombe.RNA (New York, N.Y.) · 2011Article
- Sub1 functions in osmoregulation and in transcription by both RNA polymerases II and III.Molecular and cellular biology · 2009Article
- Balanced production of ribosomal proteins.Gene · 2007Review
- Yeast cap binding complex impedes recruitment of cleavage factor IA to weak termination sites.Molecular and cellular biology · 2007Article
- Human ribosomal protein S13 regulates expression of its own gene at the splicing step by a feedback mechanism.Nucleic acids research · 2007Article
- Drosophila ribosomal proteins are associated with linker histone H1 and suppress gene transcription.Genes & development · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although it is generally accepted that transcription and translation are spatially separated in eukaryotes, a number of recent observations have called this belief into question. In particular, several studies have shown that parts of the translation machinery, including ribosomal proteins, can be found associated with sites of active transcription in metazoans. Here we describe results of chromatin immunoprecipitation (ChIP) experiments designed to determine whether ribosomal proteins associate with nascent transcripts in Saccharomyces cerevisiae and whether this association reflects a functional engagement of the translation machinery. We find that HAT-tagged ribosomal proteins can be detected in association with nascent RNAs in budding yeast. However, our data clearly indicate that this binding is independent of transcript translatability, so is therefore not indicative of nuclear translation.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.