Evidence map›Paper›PMID 16197737›Full record

ReviewHuman genomics2005

Software for quantitative trait analysis.

Laura Almasy, Diane M Warren

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Human genomics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Laura AlmasyDepartment of Genetics, Southwest Foundation for Biomedical Research, San Antonio, TX 78245-0549, USA. almasy@darwin.sfbr.org
Diane M Warren

Funding

PSYCHOPHARMACOLOGY--ORAL ALCOHOL CHALLENGE/ALCOHOL CLAMPINGU10AA008403 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI BEGLEITER, HENRI · 1989 to 2003
$23.7M
Quantitative Trait Locus Mapping in Human PedigreesR37MH059490 · NIMH · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI BLANGERO, JOHN · 2001 to 2010
$6.8M
A Neurobehavioral Family Study of SchizophreniaR01MH061622 · NIMH · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI ALMASY, LAURA A. · 2001 to 2018
$4.9M
QUANTITATIVE TRAIT LOCUS MAPPING IN HUMAN PEDIGREESR01MH059490 · NIMH · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI BLANGERO, JOHN · 1998 to 2000
$426k
NHLBI NIH HHS HL70751NIAAA NIH HHS AA08403NIMH NIH HHS MH59490NIMH NIH HHS MH61622
6 · The paper itself

Abstract

This paper provides a brief overview of software currently available for the genetic analysis of quantitative traits in humans. Programs that implement variance components, Markov Chain Monte Carlo (MCMC), Haseman-Elston (H-E) and penetrance model-based linkage analyses are discussed, as are programs for measured genotype association analyses and quantitative trait transmission disequilibrium tests. The software compared includes LINKAGE, FASTLINK, PAP, SOLAR, SEGPATH, ACT, Mx, MERLIN, GENEHUNTER, Loki, Mendel, SAGE, QTDT and FBAT. Where possible, the paper provides URLs for acquiring these programs through the internet, details of the platforms for which the software is available and the types of analyses performed.

Indexed as

Quantitative Trait LociSoftwareChromosome MappingHumansLinkage Disequilibrium

Identifiers

PMID16197737
PMCPMC3525122

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.