ReviewJournal of neuro-oncology2005
Pediatric high-grade glioma: molecular genetic clues for innovative therapeutic approaches.
Review in Journal of neuro-oncology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed.
- Magnetic Resonance Imaging Characteristics of Molecular Subgroups in Pediatric H3 K27M Mutant Diffuse Midline Glioma.Clinical neuroradiology · 2022Article
- Outcome of young children with high-grade glioma treated with irradiation-avoiding intensive chemotherapy regimens: Final report of the Head Start II and III trials.Pediatric blood & cancer · 2016Article
- Downregulation of miR-137 and miR-6500-3p promotes cell proliferation in pediatric high-grade gliomas.Oncotarget · 2016Article
- Clinical outcome and molecular characterization of pediatric glioblastoma treated with postoperative radiotherapy with concurrent and adjuvant temozolomide: a single institutional study of 66 children.Neuro-oncology practice · 2016Article
- Pathology, Molecular Genetics, and Epigenetics of Diffuse Intrinsic Pontine Glioma.Frontiers in oncology · 2015Review
- Article
- Chromatin remodeling defects in pediatric and young adult glioblastoma: a tale of a variant histone 3 tail.Brain pathology (Zurich, Switzerland) · 2013Review
- Pediatric high-grade astrocytomas: a distinct neuro-oncological paradigm.Genome medicine · 2013Review
- Clinical and molecular characteristics of congenital glioblastoma.Neuro-oncology · 2012Article
- Impact of molecular biology studies on the understanding of brain tumors in childhood.Current oncology reports · 2012Article
- Pediatric high grade glioma: a review and update on tumor clinical characteristics and biology.Frontiers in oncology · 2012Article
- Glioblastoma multiforme: Molecular characterization and current treatment strategy (Review).Experimental and therapeutic medicine · 2012Article
- Institutional experience of paediatric high-grade central nervous system tumours: an analysis of 74 patients and review of the literature.Contemporary oncology (Poznan, Poland) · 2012Article
- Prognostic significance of histological grading, p53 status, YKL-40 expression, and IDH1 mutations in pediatric high-grade gliomas.Journal of neuro-oncology · 2010Article
- Genome-wide profiling using single-nucleotide polymorphism arrays identifies novel chromosomal imbalances in pediatric glioblastomas.Neuro-oncology · 2010Article
- Mesenchymal migration as a therapeutic target in glioblastoma.Journal of oncology · 2010Article
- Pharmacokinetics of erlotinib for the treatment of high-grade glioma in a pediatric patient with cystic fibrosis: case report and review of the literature.Pharmacotherapy · 2009Article
- Modeling Adult Gliomas Using RCAS/t-va Technology.Translational oncology · 2009Article
- Congenital glioblastoma: a clinicopathologic and genetic analysis.Brain pathology (Zurich, Switzerland) · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High grade glioma remains the most intractable childhood tumor of the central nervous system. The molecular genetics of childhood high grade glioma remain largely unknown in comparison to that of their adult counterparts. In an era of molecularly targeted therapies, this dearth of knowledge will present particular challenges to those who must design and implement the next generation of therapeutic trials with these new agents. In this review, we discuss the current understanding of the molecular genetics of childhood high grade glioma and compare/contrast it to that of the adult tumors bearing the same classification for the purpose of beginning to identify the most promising therapeutic targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.