ReviewThe Journal of physiology2006
Calcium events in smooth muscles and their interstitial cells; physiological roles of sparks.
Review in The Journal of physiology, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 60 citations in OpenAlex.
- Article
- Endothelium-independent vasorelaxant effect of 20(S)-protopanaxadiol on isolated rat thoracic aorta.Acta pharmacologica Sinica · 2016Article
- Chronic stress improves NO- and Ca2+ flux-dependent vascular function: a pharmacological study.Arquivos brasileiros de cardiologia · 2015Article
- Regulation of cellular communication by signaling microdomains in the blood vessel wall.Pharmacological reviews · 2014Review
- Rhynchophylline-induced vasodilation in human mesenteric artery is mainly due to blockage of L-type calcium channels in vascular smooth muscle cells.Naunyn-Schmiedeberg's archives of pharmacology · 2013Article
- Regulation of gastrointestinal motility--insights from smooth muscle biology.Nature reviews. Gastroenterology & hepatology · 2012Review
- Hypoxic pulmonary vasoconstriction.Physiological reviews · 2012Review
- Inhibitory effect of Suaeda asparagoides (Miq.) extract on the motility of rat gastric antrum is mediated by β-adrenoceptor.Laboratory animal research · 2011Article
- NK receptors, Substance P, Ano1 expression and ultrastructural features of the muscle coat in Cav-1(-/-) mouse ileum.Journal of cellular and molecular medicine · 2011Article
- Basally activated nonselective cation currents regulate the resting membrane potential in human and monkey colonic smooth muscle.American journal of physiology. Gastrointestinal and liver physiology · 2011Article
- Ca(2+)-dependent contraction by the saponoside escin in rat vena cava: implications in venotonic treatment of varicose veins.Journal of vascular surgery · 2011Article
- Subtype identification and functional characterization of ryanodine receptors in rat cerebral artery myocytes.American journal of physiology. Cell physiology · 2010Article
- The interdependence of endothelin-1 and calcium: a review.Clinical science (London, England : 1979) · 2010Review
- Pharmacology of transient receptor potential melastatin channels in the vasculature.British journal of pharmacology · 2010Review
- Organ culture mimics the effects of hypoxia on membrane potential, K(+) channels and vessel tone in pulmonary artery.British journal of pharmacology · 2009Article
- Impaired Ca2+-dependent activation of large-conductance Ca2+-activated K+ channels in the coronary artery smooth muscle cells of Zucker Diabetic Fatty rats.Biophysical journal · 2008Article
- Long-term nitric oxide deficiency causes muscarinic supersensitivity and reduces beta(3)-adrenoceptor-mediated relaxation, causing rat detrusor overactivity.British journal of pharmacology · 2008Article
- Article
- Cholinergic innervation of the guinea-pig isolated vas deferens.Naunyn-Schmiedeberg's archives of pharmacology · 2007Article
- Ca2+-sparks constitute elementary building blocks for global Ca2+-signals in myocytes of retinal arterioles.Cell calcium · 2007Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The observation of spontaneous sporadic releases of packets of stored calcium made 20 years ago has opened up a number of new concepts in smooth muscle physiology: (1) the calcium release sites are ryanodine and inositol 1,4,5-trisphosphate (IP3) receptor channels which contribute to cell-wide increases in [Ca2+]i in response to cell depolarization, activation of IP3-generating receptors, or other stimuli; (2) changes in [Ca2+]i act back on the cell membrane to activate or modulate K+, Cl- and cation channel activity so affecting contraction, in arterial smooth muscle for example affecting blood pressure; (3) IP3 production is voltage dependent and is believed to contribute to pacemaker potentials and to refractory periods which control the rhythmical motility of many hollow organs. Most smooth muscle tissues contain interstitial cells (ICs) in addition to contractile smooth muscle cells (SMCs). The interactions of these internal mechanisms, and in turn the interactions of SMCs and ICs in various smooth muscle tissues, are major factors in determining the unique physiological profiles of individual smooth muscles.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.