ArticleHuman genetics2005
Examination of ancestry and ethnic affiliation using highly informative diallelic DNA markers: application to diverse and admixed populations and implications for clinical epidemiology and forensic medicine.
Article in Human genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers.
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Who cites it
77 citing papers in PubMed.
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- Considering microRNAs as measures of extrinsic domains of risk in the context of underlying genetic characteristics: type 2 diabetes as an exemplar.Frontiers in genetics · 2026Article
- Racial-Ethnic disparities in stroke prevalence among patients with heart failure.Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia · 2024Article
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- Copy Number Variation and Frequency of rs179008 inJournal of immunology research · 2022Article
- Undercutting efforts of precision medicine: roadblocks to minority representation in breast cancer clinical trials.Breast cancer research and treatment · 2021Review
- Gene-Environment Interaction between theInternational journal of environmental research and public health · 2020Article
- Ancestry informative markers (AIMs) for Korean and other East Asian and South East Asian populations.International journal of legal medicine · 2019Article
- Relationship between West African ancestry with lung cancer risk and survival in African Americans.Cancer causes & control : CCC · 2019Article
- The three-hybrid genetic composition of an Ecuadorian population using AIMs-InDels compared with autosomes, mitochondrial DNA and Y chromosome data.Scientific reports · 2019Article
- Inferring biogeographic ancestry with compound markers of slow and fast evolving polymorphisms.European journal of human genetics : EJHG · 2018Article
- Autosomal DIPs for population genetic structure and differentiation analyses of Chinese Xinjiang Kyrgyz ethnic group.Scientific reports · 2018Article
- Comparative tolerance of two massively parallel sequencing systems to common PCR inhibitors.International journal of legal medicine · 2018Article
- Serological and molecular analysis of parvovirus B19 infection in Mayan women with systemic lupus erythematosus in Mexico.Colombia medica (Cali, Colombia) · 2017Article
- Article
- Empirical testing of a 23-AIMs panel of SNPs for ancestry evaluations in four major US populations.International journal of legal medicine · 2016Article
- A minimum set of ancestry informative markers for determining admixture proportions in a mixed American population: the Brazilian set.European journal of human genetics : EJHG · 2016Article
- Selection of highly informative SNP markers for population affiliation of major US populations.International journal of legal medicine · 2016Article
- Population genetic structure analysis and forensic evaluation of Xinjiang Uigur ethnic group on genomic deletion and insertion polymorphisms.SpringerPlus · 2016Article
17 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
We and others have identified several hundred ancestry informative markers (AIMs) with large allele frequency differences between different major ancestral groups. For this study, a panel of 199 widely distributed AIMs was used to examine a diverse set of 796 DNA samples including self-identified European Americans, West Africans, East Asians, Amerindians, African Americans, Mexicans, Mexican Americans, Puerto Ricans and South Asians. Analysis using a Bayesian clustering algorithm (STRUCTURE) showed grouping of individuals with similar ethnic identity without any identifier other than the AIMs genotyping and showed admixture proportions that clearly distinguished different individuals of mixed ancestry. Additional analyses showed that, for the majority of samples, the predicted ethnic identity corresponded with the self-identified ethnicity at high probability (P > 0.99). Overall, the study demonstrates that AIMs can provide a useful adjunct to forensic medicine, pharmacogenomics and disease studies in which major ancestry or ethnic affiliation might be linked to specific outcomes.
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