ArticleProceedings. Biological sciences2005
Population size and molecular evolution on islands.
Article in Proceedings. Biological sciences, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
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Who cites it
79 citing papers in PubMed.
- Multiple drivers of genomic novelty across ruminants.iScience · 2026Article
- Positive and relaxed selection on mitochondrial DNA in parasitic versus predatory mites.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Article
- Lifespan Predicts Mitochondrial Substitution Rates across Vertebrates, but Methodology Matters.Genome biology and evolution · 2026Article
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- Diverse mitogenomic variations contribute to population differentiation in Eurasian tree sparrows (Zoological research · 2026Article
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- Evolution and ecology of body size in the world's largest bats.Proceedings. Biological sciences · 2025Article
- Stronger Evidence for Relaxed Selection Than Adaptive Evolution in High-elevation Animal mtDNA.Molecular biology and evolution · 2025Article
- Genomes of Galápagos Mockingbirds Reveal the Impact of Island Size and Past Demography on Inbreeding and Genetic Load in Contemporary Populations.Molecular ecology · 2025Article
- ZW Sex Chromosome Differentiation in Palaeognathous Birds Is Associated with Mitochondrial Effective Population Size but Not Mitochondrial Genome Size or Mutation Rate.Genome biology and evolution · 2025Article
- Elevated Rates of Molecular Evolution Genome-wide in Mutualist Legumes and Rhizobia.Molecular biology and evolution · 2024Article
- Genomic Gigantism is not Associated with Reduced Selection Efficiency in Neotropical Salamanders.Journal of molecular evolution · 2024Article
- Conservation Mitonuclear Replacement: Facilitated mitochondrial adaptation for a changing world.Evolutionary applications · 2024Article
- Stronger evidence for relaxed selection than adaptive evolution in high-elevation animal mtDNA.bioRxiv : the preprint server for biology · 2024Article
- Assessment of genetic conservation units of an endangered glacial relict insular species,Frontiers in plant science · 2024Article
- Genomic signatures of convergent shifts to plunge-diving behavior in birds.Communications biology · 2023Article
- Disentangling Positive Selection from Relaxed Selection in Animal Mitochondrial Genomes.The American naturalist · 2023Article
- Insights into the Genomics of Clownfish Adaptive Radiation: The Genomic Substrate of the Diversification.Genome biology and evolution · 2023Article
- Genomic footprints of bottleneck in landlocked salmon population.Scientific reports · 2023Article
- Genome structure-based Juglandaceae phylogenies contradict alignment-based phylogenies and substitution rates vary with DNA repair genes.Nature communications · 2023Article
19 more citing papers are in PubMed but not listed here.
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2 authors.
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Abstract
The nearly neutral theory predicts that the rate and pattern of molecular evolution will be influenced by effective population size (Ne), because in small populations more slightly deleterious mutations are expected to drift to fixation. This important prediction has not been widely empirically tested, largely because of the difficulty of comparing rates of molecular evolution in sufficient numbers of independent lineages which differ only in Ne. Island endemic species provide an ideal test of the effect of Ne on molecular evolution because species restricted to islands frequently have smaller Ne than closely related mainland species, and island endemics have arisen from mainland lineages many times in a wide range of taxa. We collated a dataset of 70 phylogenetically independent comparisons between island and mainland taxa, including vertebrates, invertebrates and plants, from 19 different island groups. The rate of molecular evolution in these lineages was estimated by maximum likelihood using two measures: overall substitution rate and the ratio of non-synonymous to synonymous substitution rates. We show that island lineages have significantly higher ratios of non-synonymous to synonymous substitution rates than mainland lineages, as predicted by the nearly neutral theory, although overall substitution rates do not differ significantly.
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