ArticleJournal of anatomy2005
Non-vascular smooth muscle cells in the human choroid: distribution, development and further characterization.
Article in Journal of anatomy, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.
- Choroidal Thickness and Its Association With Age, Axial Length, and Refractive Error in Chinese Adults.Investigative ophthalmology & visual science · 2022Pooled it
- The Effect of Light Intensity and the Timing of Light Exposure on Choroidal Thickness.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026Trial
- Volumetric choroidal biomarkers in central serous chorioretinopathy using swept-source optical coherence tomography: a deep learning approach.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Short-Term Choroidal and Retinal Structural Changes in Myopic Children Treated with 0.05% Atropine.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Age-Related Regional Changes in Choroidal Vascularity in Healthy Emmetropic Eyes.Translational vision science & technology · 2025Article
- Corneal higher-order aberrations and their relationship with choroid in myopic patients.BMC ophthalmology · 2024Article
- Differences in choroidal responses to near work between myopic children and young adults.Eye and vision (London, England) · 2024Article
- Quantitative Evaluation of the Topographical Maps of Three-Dimensional Choroidal Vascularity Index in Children With Different Degrees of Myopia.Investigative ophthalmology & visual science · 2024Article
- IMI-The Dynamic Choroid: New Insights, Challenges, and Potential Significance for Human Myopia.Investigative ophthalmology & visual science · 2023Review
- Evaluation of Choroidal Vascular Structure in Hyperopic Anisometropic Amblyopia.Beyoglu eye journal · 2023Article
- Ultra-Widefield Swept-Source Optical Coherence Tomography Angiography in the Assessment of Choroidal Changes in Young Adults With Myopia.Translational vision science & technology · 2022Article
- Shining a light on foveal development after congenital cataract surgery.Annals of translational medicine · 2022Article
- The choroid-sclera interface: An ultrastructural study.Heliyon · 2022Article
- Choroidal and Retinal Thickness and Axial Eye Elongation in Chinese Junior Students.Investigative ophthalmology & visual science · 2021Observational
- Choroidal Vascularity Map in Unilateral Central Serous Chorioretinopathy: A Comparison with Fellow and Healthy Eyes.Diagnostics (Basel, Switzerland) · 2021Article
- IMI Accommodation and Binocular Vision in Myopia Development and Progression.Investigative ophthalmology & visual science · 2021Review
- Macular irregularities of optical coherence tomographic vertical cross sectional images in school age children.Scientific reports · 2021Observational
- Applications of Multimodal Imaging in Central Serous Chorioretinopathy Evaluation.Journal of ophthalmology · 2021Review
- Current Choroidal Imaging Findings in Central Serous Chorioretinopathy.Vision (Basel, Switzerland) · 2020Review
- Analysis of Choroidal Vascularity in Children with Unilateral Hyperopic Amblyopia.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To characterize further non-vascular smooth muscle cells (NVSMC) in the choroid of the human eye, extensive morphological studies were performed including a three-dimensional distribution of NVSMC in the adult human eye and their appearance during development. Whole mounts and sections through the choroid and sclera of eyes of 42 human donors (between the 13th week of gestation and 89 years of age) were stained with antibodies against smooth muscle actin and other markers for smooth muscle cells. On the basis of their morphological localization, three groups of NVSMC could be distinguished in the adult eyes: (a) a semicircular arrangement of NVSMC in the suprachoroid and inner sclera, around the entry of posterior ciliary arteries and nerves; (b) NVSMC parallel to the vessels in the posterior eye segment between the point of entry of the posterior ciliary arteries and the point of exit of the vortex veins; and (c) a dense plaque-like arrangement of NVSMC in the suprachoroid, overlying the foveal region. The last of these groups showed most pronounced interindividual differences. During development, the first NVSMC to be observed at the 20th week of gestation belonged to group b. A complete NVSMC network was first observed in a 6-year-old donor eye. All three groups stained positive for smoothelin, caldesmon and calponin in all localizations. The NVSMC show a distinct distribution that might reflect different aspects of their function in the choroid and suprachoroid. All cells could be histochemically characterized as truly contractile.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.