ArticleDigestive diseases and sciences2005
Sensorineural hearing loss in patients with inflammatory bowel disease: a subclinical extraintestinal manifestation.
Article in Digestive diseases and sciences, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 62 citations in OpenAlex.
- A case of cryopyrin-associated periodic syndrome presenting with abdominal symptoms due to a novel mutation NLRP3 p.Ile257Met.Clinical journal of gastroenterology · 2026Article
- Article
- Is routine hearing screening necessary in patients with inflammatory bowel disease - a prospective study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Oculomotor nerve palsy as an extraintestinal manifestation of Crohn's disease.BMJ case reports · 2023Article
- A review of the auditory-gut-brain axis.Frontiers in neuroscience · 2023Review
- A High-Fat Diet Induces Low-Grade Cochlear Inflammation in CD-1 Mice.International journal of molecular sciences · 2022Article
- Sensorineural hearing loss and ulcerative colitis in remission.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2022Observational
- The Link between Gut Dysbiosis Caused by a High-Fat Diet and Hearing Loss.International journal of molecular sciences · 2021Review
- Assessment of Hearing Function in Children with Inflammatory Bowel Disease.The journal of international advanced otology · 2020Article
- Ear Involvement in Inflammatory Bowel Disease: A Review of the Literature.Journal of clinical medicine research · 2018Review
- Ocular, Auricular, and Oral Manifestations of Inflammatory Bowel Disease.Digestive diseases and sciences · 2017Review
- Hearing Loss in Patients with Inflammatory Bowel Disease.Digestive diseases and sciences · 2016Article
- Symptomatic sensorineural hearing loss in patients with ulcerative colitis.Techniques in coloproctology · 2015Article
- Sensorineural hearing loss in pediatric patients with celiac disease.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2015Article
- Sensorineural hearing loss and status epilepticus associated with ulcerative colitis: Is there enough evidence to support immune-related mechanisms?Journal of neurosciences in rural practice · 2015Article
- Neurological disorders and inflammatory bowel diseases.World journal of gastroenterology · 2014Review
- [Neurological complications of inflammatory bowel diseases].Der Nervenarzt · 2013Review
- Sensorineural hearing loss in pediatric patients with inflammatory bowel disease.Digestive diseases and sciences · 2010Article
- Extraintestinal manifestations and complications in inflammatory bowel diseases.World journal of gastroenterology · 2006Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Isolated case reports in which symptomatic hearing loss develops suddenly during the course of inflammatory bowel disease (IBD) have been reported, but the presence of subclinical sensorineural hearing loss (SNHL) associated with IBD has been investigated in only two preliminary studies. In order to research this further, we aimed to investigate the presence of subclinical SNHL in IBD by comparison with a control group and to examine possible relations between the bowel disease parameters and hearing loss.Otoscopy, tympanometry, and pure tone audiometry were carried out in 39 patients with IBD (21 Crohn's disease [CD], 18 ulcerative colitis [UC]) and 25 healthy age- and sex-matched controls. All patients and control subjects had normal otoscopy findings and tympanometry was unremarkable, excluding middle ear disease and conductive hearing loss. Analysis of each frequency examined showed that the average hearing thresholds were increased significantly in the study group compared to those of the control group at higher frequencies (2, 4, and 8 kHz). When these parameters were compared with the control group according to subgroups of IBD, a significant difference was determined for the UC group at frequencies of 2, 4, and 8 kHz and for the CD group only at the frequency of 4 kHz. Although there was a trend of increment in SNHL as the age of the patient and duration and extent of UC increased, no significant correlation was observed between SNHL and these parameters or sex, activity, involvement site, medication history of IBD, and coexistence of other extraintestinal manifestations. In conclusion, it was demonstrated that a subclinical SNHL may be associated with UC and somewhat with CD, affecting mainly the high frequencies. In light of this finding, it may be advisable to investigate labyrinth functions as well as other extraintestinal manifestations in patients with IBD.
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