ReviewDigestive diseases and sciences2005
Cellular and molecular mechanisms of the epithelial repair in IBD.
Review in Digestive diseases and sciences, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 74 citations in OpenAlex.
- Cellular Plasticity in Gut and Liver Regeneration.Gut and liver · 2024Review
- Epithelial restitution in 3D - Revealing biomechanical and physiochemical dynamics in intestinal organoids via fs laser nanosurgery.iScience · 2023Article
- Crohn's Disease: Basic Characteristics of the Disease, Diagnostic Methods, the Role of Biomarkers, and Analysis of Metalloproteinases: A Review.Life (Basel, Switzerland) · 2023Review
- Article
- Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal.Cell stem cell · 2022Article
- Organoid-based regenerative medicine for inflammatory bowel disease.Regenerative therapy · 2020Review
- Article
- G-protein-coupled receptor kinase-2 is a critical regulator of TNFα signaling in colon epithelial cells.The Biochemical journal · 2017Article
- Epithelial Cell-Derived a Disintegrin and Metalloproteinase-17 Confers Resistance to Colonic Inflammation Through EGFR Activation.EBioMedicine · 2016Article
- Role of epithelial cells in the pathogenesis and treatment of inflammatory bowel disease.Journal of gastroenterology · 2016Review
- Investigation of sesamol on myeloperoxidase and colon morphology in acetic acid-induced inflammatory bowel disorder in albino rats.TheScientificWorldJournal · 2014Article
- Article
- The possible role of mesenchymal stem cells therapy in the repair of experimentally induced colitis in male albino rats.International journal of stem cells · 2013Article
- Macrophages promote epithelial repair through hepatocyte growth factor secretion.Clinical and experimental immunology · 2013Article
- The digestive neuronal-glial-epithelial unit: a new actor in gut health and disease.Nature reviews. Gastroenterology & hepatology · 2013Review
- Multifunctional role of dextran sulfate sodium for in vivo modeling of intestinal diseases.BMC immunology · 2012Article
- Bin1: a new player in IBD barrier dysfunction.Digestive diseases and sciences · 2012Article
- The N-terminal fragment of chromogranin A, vasostatin-1 protects mice from acute or chronic colitis upon oral administration.Digestive diseases and sciences · 2012Article
- Article
- Chemokine stimulation promotes enterocyte migration through laminin-specific integrins.American journal of physiology. Gastrointestinal and liver physiology · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Inflammatory bowel diseases such as ulcerative colitis or Crohn's disease frequently cause epithelial damage in the intestine. In general, the intestinal epithelium is able to rapidly repair itself by the restitution, proliferation, and differentiation of epithelial cells when such tissue damage occurs. However, severe and continuous inflammation could disturb the intrinsic repair system, resulting in refractory ulcers in the intestine. In this review, we will describe the recent findings of the cellular and molecular mechanisms regulating the regeneration process of the intestinal epithelium. Furthermore, we will propose bone marrow cells as a novel source of cells to regenerate the damaged intestinal epithelium. Bone marrow cells are the only cells of extra-gastrointestinal origin that are shown to contribute to the regeneration of the intestinal epithelium. Further studies of these cells and molecules may lead to a novel therapy for the repair of damaged intestinal epithelium.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.