Evidence map›Paper›PMID 16184413›Full record

Trial reportDigestive diseases and sciences2005

Rebamipide enemas-new effective treatment for patients with corticosteroid dependent or resistant ulcerative colitis.

Mitsuki Miyata, Kunio Kasugai, Tetsuya Ishikawa, Shinichi Kakumu, Masafumi Onishi, Takeshi Mori

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Digestive diseases and sciences, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

  1. Trial
  2. Article
  3. Novel topical therapies for distal colitis.World journal of gastrointestinal pharmacology and therapeutics · 2010
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Mitsuki MiyataDepartment of Gastroenterology, Aichi Medical University School of Medicine, Aichi-Gun, Aichi 480-1195, Japan. mmiyata@ aichi-med-u.ac.jp
Kunio Kasugai
Tetsuya Ishikawa
Shinichi Kakumu
Masafumi Onishi
Takeshi Mori
Aichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study we investigated the effect of rebamipide enema in patients with steroid-resistant and/or dependent ulcerative colitis. Rebamipide enemas were administered twice daily for a 12-week period; this treatment was further continued longer in patients who requested this. Disease activity index as reflecting the clinical condition and endoscopic index with histological grading were determined before and after the treatment period. Nine of 11 (81.8%) patients on 12-week treatment with rebamipide approved and were classified as colitis in remission. Moreover, seven of 11 patients requested long-term medication, the longest medication term being 80 weeks. These results medicated that rebamipide enemas may be effective in patients with steroid-resistant and/or dependent ulcerative colitis.

Indexed as

AdolescentAdrenal Cortex HormonesAdultAlanineAnti-Ulcer AgentsColitis, UlcerativeDrug ResistanceEnemaFemaleHumansMaleMiddle AgedPatient SatisfactionQuinolonesSeverity of Illness IndexAdrenal Cortex HormonesAlanineAnti-Ulcer AgentsQuinolonesrebamipide

Identifiers

PMID16184413
OpenAlexW2041879233

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.