Evidence map›Paper›PMID 16184386›Full record

ArticlePlant cell reports2006

Translation initiation by non-AUG codons in Arabidopsis thaliana transgenic plants.

Annie Depeiges, Fabienne Degroote, Marie Claude Espagnol, Georges Picard

Abstract read
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In one paragraph

Article in Plant cell reports, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Evaluating Plant Gene Models Using Machine Learning.Plants (Basel, Switzerland) · 2022
    Article
  2. Codon usage bias.Molecular biology reports · 2022
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Annie DepeigesUMR 6547 CNRS GEEM-BIOMOVE, Université Blaise Pascal, 24 avenue des Landais, 63177 Aubière, France. Annie.DEPEIGES@univ-bpclermont.fr
Fabienne Degroote
Marie Claude Espagnol
Georges Picard
Université Clermont Auvergne · FRCentre National de la Recherche Scientifique · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The efficiency of translation initiation at codons differing at one or two nucleotides from AUG was tested as initiation codons for the phosphinotricin-acetyltransferase gene in T-DNA plant transformation in Arabidopsis thaliana. With the exception of UUA codon that differs from AUG at two nucleotides and does not permit any detectable activity, all the other codons (AUC, GUG, ACG, and CUG) present a phosphinotrycin acetyltransferase activity that varies between 5 and 10% of the AUG activity. This low activity is sufficient to confer glufosinate resistance to some of the plants. These results indicate that, in plants as is the case in animals, non-AUG initiating codons may be used for translation initiation, namely when a low expression rate is needed.

Indexed as

AcetyltransferasesAminobutyratesArabidopsisCodon, InitiatorDNA, BacterialPeptide Chain Initiation, TranslationalPhenotypePlants, Genetically ModifiedSeedlingsAcetyltransferasesAminobutyratesCodon, InitiatorDNA, BacterialphosphinothricinT-DNA

Identifiers

PMID16184386
OpenAlexW2064406838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.