ArticlePlant physiology2005
Allelic series of four powdery mildew resistance genes at the Pm3 locus in hexaploid bread wheat.
Article in Plant physiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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Who cites it
66 citing papers in PubMed.
- Unlocking the genetic control of early seedling resistance to wheat powdery mildew through microphenomics.Pest management science · 2026Article
- Susceptibility of durum wheat to Fusarium graminearum, Blumeria graminis f.sp. tritici, and Zymoseptoria tritici in Poland.Scientific reports · 2025Article
- An NLR pair in the Pm68 locus confers powdery mildew resistance in durum and common wheat.Nature communications · 2025Article
- Discovery of functional NLRs using expression level, high-throughput transformation and large-scale phenotyping.Nature plants · 2025Article
- Progress and innovations of gene cloning in wheat and its close relatives.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Review
- The Wheat NLR Protein PM3b Localises to Endoplasmic Reticulum-Plasma Membrane Contact Sites and Interacts With AVRPM3Molecular plant pathology · 2025Article
- Molecular identification of a Pm4 allele conferring powdery mildew resistance in durum wheat DR88.BMC plant biology · 2024Article
- Review
- Article
- Breeding for durable resistance against biotrophic fungal pathogens using transgenes from wheat.Molecular breeding : new strategies in plant improvement · 2024Article
- Exploring the genetic architecture of powdery mildew resistance in wheat through QTL meta-analysis.Frontiers in plant science · 2024Article
- Bulked segregant RNA-seq reveals complex resistance expression profile to powdery mildew in wild emmer wheat W762.Frontiers in plant science · 2024Article
- Single amino acid change alters specificity of the multi-allelic wheat stem rust resistance locus SR9.Nature communications · 2023Article
- Fighting wheat powdery mildew: from genes to fields.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2023Review
- Structural polymorphisms within a common powdery mildew effector scaffold as a driver of coevolution with cereal immune receptors.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Contribution of Duplicated Nucleotide-Binding Leucine-Rich Repeat (NLR) Genes to Wheat Disease Resistance.Plants (Basel, Switzerland) · 2023Review
- Integrated Molecular and Bioinformatics Approaches for Disease-Related Genes in Plants.Plants (Basel, Switzerland) · 2023Review
- Magnaporthe oryzae pathotype Triticum (MoT) can act as a heterologous expression system for fungal effectors with high transcript abundance in wheat.Scientific reports · 2023Article
- Wheat powdery mildew resistance: from gene identification to immunity deployment.Frontiers in plant science · 2023Review
- An interolog-based barley interactome as an integration framework for immune signaling.Genetics · 2022Article
6 more citing papers are in PubMed but not listed here.
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4 authors.
Funding
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Abstract
At the Pm3 locus in hexaploid wheat (Triticum aestivum), 10 alleles conferring race-specific resistance to powdery mildew (Blumeria graminis f. sp. tritici) are known. A cluster of genes encoding coiled-coil-nucleotide-binding site-leucine-rich repeat proteins spans the Pm3 locus on wheat chromosome 1A, and one member of this gene family has recently been identified as the Pm3b resistance gene. Using molecular markers closely linked to Pm3b, we performed haplotype analysis of 10 lines carrying different Pm3 alleles. All these lines have a conserved genomic region delimited by markers cosegregating with Pm3b and including a structurally conserved Pm3b-like gene. A polymerase chain reaction-based strategy allowed the amplification of one Pm3b-like sequence from lines carrying Pm3a, Pm3d, and Pm3f alleles. These candidate genes for Pm3a, Pm3d, and Pm3f conferred AvrPm3a-, AvrPm3d-, and AvrPm3f-dependent resistance, respectively, to wheat powdery mildew in a single cell transient transformation assay. A high level of amino acid similarity (97.8%) was found between the PM3A, PM3B, PM3D, and PM3F proteins. The coiled-coil domain was 100% conserved, whereas, in the nucleotide binding site region, sequence exchange was detected, indicating intragenic recombination or gene conversion between alleles. All these results indicate that Pm3a, Pm3b, Pm3d, and Pm3f form a true allelic series. The low level of sequence divergence between the four characterized alleles as well as the finding of a conserved Pm3 haplotype are in agreement with the hypothesis of a recent evolution of Pm3-based resistance, suggesting that some or most of the diversity found at the Pm3 locus in modern wheat has evolved after wheat domestication.
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