Evidence map›Paper›PMID 16182587›Full record

ReviewMicrobes and infection2006

Perspective on the host response to human metapneumovirus infection: what can we learn from respiratory syncytial virus infections?

Surendran Mahalingam, Jurgen Schwarze, Ali Zaid, Michael Nissen, Theo Sloots, Sharyn Tauro, James Storer, Rene Alvarez, Ralph A Tripp

Abstract readReview
In one paragraph

Review in Microbes and infection, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Viral infections in lung transplant recipients.Seminars in respiratory and critical care medicine · 2010
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Surendran MahalingamViral Arthritis/Asthma Research Group, School of Health Sciences, University of Canberra, Canberra, ACT 2601, Australia. suresh.mahalingam@canberra.edu.au
Jurgen Schwarze
Ali Zaid
Michael Nissen
Theo Sloots
Sharyn Tauro
James Storer
Rene Alvarez
Ralph A Tripp

Funding

Wellcome Trust
6 · The paper itself

Abstract

Human metapneumovirus (HMPV) is a recently discovered pathogen first identified in respiratory specimens from young children suffering from clinical respiratory syndromes ranging from mild to severe lower respiratory tract illness. HMPV has worldwide prevalence, and is a leading cause of respiratory tract infection in the first years of life, with a spectrum of disease similar to respiratory syncytial virus (RSV). The disease burden associated with HMPV infection has not been fully elucidated; however, studies indicate that HMPV may cause upper or lower respiratory tract illness in patients between ages 2 months and 87 years, may co-circulate with RSV, and HMPV infection may be associated with asthma exacerbation. The mechanisms and effector pathways contributing to immunity or disease pathogenesis following infection are not fully understood; however, given the clinical significance of HMPV, there is a need for a fundamental understanding of the immune and pathophysiological processes that occur following infection to provide the foundation necessary for the development of effective vaccine or therapeutic intervention strategies. This review provides a current perspective on the processes associated with HMPV infection, immunity, and disease pathogenesis.

Indexed as

AsthmaHumansMetapneumovirusParamyxoviridae InfectionsRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus Infections

Identifiers

PMID16182587
PMCPMC7110670

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.