ArticleMammalian genome : official journal of the International Mammalian Genome Society2005
Fine mapping of the polled locus to a 1-Mb region on bovine chromosome 1q12.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Welfare of beef cattle.EFSA journal. European Food Safety Authority · 2025Article
- The Future of Livestock Management: A Review of Real-Time Portable Sequencing Applied to Livestock.Genes · 2020Review
- A de novo frameshift mutation in ZEB2 causes polledness, abnormal skull shape, small body stature and subfertility in Fleckvieh cattle.Scientific reports · 2020Article
- Characterization of the poll allele in Brahman cattle using long-read Oxford Nanopore sequencing.Journal of animal science · 2020Article
- Are scurs in heterozygous polled (Pp) cattle a complex quantitative trait?Genetics, selection, evolution : GSE · 2020Article
- Simultaneous introgression of three POLLED mutations into a synthetic breed of Chinese cattle.PloS one · 2017Article
- Revealing misassembled segments in the bovine reference genome by high resolution linkage disequilibrium scan.BMC genomics · 2016Article
- Genomic signatures reveal new evidences for selection of important traits in domestic cattle.Molecular biology and evolution · 2015Article
- An interpretive review of selective sweep studies in Bos taurus cattle populations: identification of unique and shared selection signals across breeds.Frontiers in genetics · 2015Review
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- The 80-kb DNA duplication on BTA1 is the only remaining candidate mutation for the polled phenotype of Friesian origin.Genetics, selection, evolution : GSE · 2014Article
- Identification of selection signatures in livestock species.Genetics and molecular biology · 2014Review
- Independent polled mutations leading to complex gene expression differences in cattle.PloS one · 2014Article
- Detection of selective sweeps in cattle using genome-wide SNP data.BMC genomics · 2013Article
- Article
- A Single Nucleotide Polymorphism within the Interferon Gamma Receptor 2 Gene Perfectly Coincides with Polledness in Holstein Cattle.PloS one · 2013Article
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- Article
- A newly described bovine type 2 scurs syndrome segregates with a frame-shift mutation in TWIST1.PloS one · 2011Article
- Identification of selection signatures in cattle breeds selected for dairy production.Genetics · 2010Article
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4 authors.
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Abstract
The absence of horns in Bos taurus is under genetic control of the autosomal dominant polled locus which has been genetically mapped to the centromeric region of cattle Chromosome 1. Recently a 4-Mb BAC contig of this chromosomal region has been constructed. Toward positional cloning of the bovine polled locus, we identified 20 additional microsatellite markers spread over the contig map by random sequencing of bacterial artificial chromosome (BAC) subclones. A total of 26 markers were genotyped in 30 two-generation half-sib families of six different German cattle breeds segregating for the hornless phenotype including 336 informative meioses for the polled character. Our fine-mapping study involving 19 recombinant haplotypes allowed us to narrow the critical region for the bovine polled locus to a 1-Mb segment with a centromeric boundary at RP42-218J17_MS1 and a telomeric boundary at BM6438. For marker-assisted selection purposes, the first evidence of informative flanking markers helps to predict polled genotypes with a higher degree of accuracy within families until testing of the causative mutation is available.
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