ArticleInfection and immunity2005
Relationship of virulence factor expression to evolved virulence in mouse-passaged Cryptococcus neoformans lines.
Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed.
- Quantification of C. neoformans Capsule Diameter.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Article
- Size Matters: Measurement of Capsule Diameter in Cryptococcus neoformans.Journal of visualized experiments : JoVE · 2018Article
- It's not all about us: evolution and maintenance of Cryptococcus virulence requires selection outside the human host.Yeast (Chichester, England) · 2017Article
- Article
- Cryptococcus gattii VGIII isolates causing infections in HIV/AIDS patients in Southern California: identification of the local environmental source as arboreal.PLoS pathogens · 2014Article
- Article
- Article
- A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients.PLoS pathogens · 2011Article
- Cryptococcus neoformans responds to mannitol by increasing capsule size in vitro and in vivo.Cellular microbiology · 2010Article
- Most environmental isolates of Cryptococcus neoformans var. grubii (serotype A) are not lethal for mice.Infection and immunity · 2009Article
- Evaluation of the experimental inoculation of Cryptococcus albidus and Cryptococcus laurentii in normal mice: virulence factors and molecular profile before and after animal passage.Mycopathologia · 2009Article
- New insights on the pathogenesis of invasive Cryptococcus neoformans infection.Current infectious disease reports · 2007Article
- Estimating the relative contributions of virulence factors for pathogenic microbes.Infection and immunity · 2006Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Serial passage of Cryptococcus neoformans in mice increases virulence relative to the nonpassaged line. Postpassaged lines showed no difference in the expression of most known virulence factors, with the exception that the more virulent lines had smaller capsules in vitro. These data imply that other mechanisms of virulence remain to be discovered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.