ArticleInfection and immunity2005
Cloning vectors and fluorescent proteins can significantly inhibit Salmonella enterica virulence in both epithelial cells and macrophages: implications for bacterial pathogenesis studies.
Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 61 citations in OpenAlex.
- A versatile dual-color bacterial reporter system highlights two distinctApplied and environmental microbiology · 2026Article
- Nature and consequences of interactions between Salmonella enterica serovar Dublin and host cells in cattle.Veterinary research · 2019Article
- Predicting bacterial infection outcomes using single cell RNA-sequencing analysis of human immune cells.Nature communications · 2019Article
- Review
- Avian PathogenicFrontiers in immunology · 2019Article
- Floxed-Cassette Allelic Exchange Mutagenesis Enables Markerless Gene Deletion in Chlamydia trachomatis and Can Reverse Cassette-Induced Polar Effects.Journal of bacteriology · 2018Article
- Salmonella Typhimurium Infection of Human Monocyte-Derived Macrophages.Current protocols in microbiology · 2018Article
- A Multicolor Split-Fluorescent Protein Approach to Visualize Listeria Protein Secretion in Infection.Biophysical journal · 2018Article
- Proteogenomics in Aid of Host-Pathogen Interaction Studies: A Bacterial Perspective.Proteomes · 2017Review
- Optimized Fluorescence Complementation Platform for Visualizing Salmonella Effector Proteins Reveals Distinctly Different Intracellular Niches in Different Cell Types.ACS infectious diseases · 2017Article
- Predictable, Tunable Protein Production inFrontiers in cellular and infection microbiology · 2017Article
- Long-term live-cell imaging reveals new roles for Salmonella effector proteins SseG and SteA.Cellular microbiology · 2017Article
- SopB-Mediated Recruitment of SNX18 FacilitatesFrontiers in cellular and infection microbiology · 2017Article
- Identification of vacuoles containing extraintestinal differentiated forms of Legionella pneumophila in colonized Caenorhabditis elegans soil nematodes.MicrobiologyOpen · 2015Article
- Deciphering why Salmonella Gallinarum is less invasive in vitro than Salmonella Enteritidis.Veterinary research · 2014Article
- Article
- Dimethyl adenosine transferase (KsgA) deficiency in Salmonella enterica Serovar Enteritidis confers susceptibility to high osmolarity and virulence attenuation in chickens.Applied and environmental microbiology · 2013Article
- Article
- Automated analysis of cryptococcal macrophage parasitism using GFP-tagged cryptococci.PloS one · 2010Article
- Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella.The EMBO journal · 2010Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Plasmid vectors and fluorescent protein reporter systems are commonly used in the study of bacterial pathogenesis. Here we show that they can impair the ability of Salmonella enterica serovar Typhimurium to productively infect either cultured mammalian cells or mice. This has significant implications for studies that rely on these systems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.