ArticleInfection and immunity2005
Clearance of Bordetella parapertussis from the lower respiratory tract requires humoral and cellular immunity.
Article in Infection and immunity, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 29 citations in OpenAlex.
- Article
- Article
- Outer-Membrane-Vesicle-Associated O Antigen, a Crucial Component for Protecting AgainstFrontiers in immunology · 2018Article
- Bordetella parapertussis Circumvents Neutrophil Extracellular Bactericidal Mechanisms.PloS one · 2017Article
- Functional Immune Cell Differences Associated With Low Vaccine Responses in Infants.The Journal of infectious diseases · 2016Article
- Resident microbiota affect Bordetella pertussis infectious dose and host specificity.The Journal of infectious diseases · 2014Article
- Bordetella parapertussis survives the innate interaction with human neutrophils by impairing bactericidal trafficking inside the cell through a lipid raft-dependent mechanism mediated by the lipopolysaccharide O antigen.Infection and immunity · 2012Article
- Lack of cross-protection against Bordetella holmesii after pertussis vaccination.Emerging infectious diseases · 2012Article
- Functional deficits of pertussis-specific CD4+ T cells in infants compared to adults following DTaP vaccination.Clinical and experimental immunology · 2012Article
- Decreased leukocyte accumulation and delayed Bordetella pertussis clearance in IL-6-/- mice.Journal of immunology (Baltimore, Md. : 1950) · 2011Article
- Acellular pertussis vaccination facilitates Bordetella parapertussis infection in a rodent model of bordetellosis.Proceedings. Biological sciences · 2010Article
- IL-10 induction by Bordetella parapertussis limits a protective IFN-gamma response.Journal of immunology (Baltimore, Md. : 1950) · 2010Article
- The O antigen is a critical antigen for the development of a protective immune response to Bordetella parapertussis.Infection and immunity · 2009Article
- Article
- Bordetella pertussis infection or vaccination substantially protects mice against B. bronchiseptica infection.PloS one · 2009Article
- Inefficient Toll-like receptor-4 stimulation enables Bordetella parapertussis to avoid host immunity.PloS one · 2009Article
- Replacement of adenylate cyclase toxin in a lineage of Bordetella bronchiseptica.Journal of bacteriology · 2008Article
- O antigen protects Bordetella parapertussis from complement.Infection and immunity · 2008Article
- The O antigen enables Bordetella parapertussis to avoid Bordetella pertussis-induced immunity.Infection and immunity · 2007Article
- Comparative role of immunoglobulin A in protective immunity against the Bordetellae.Infection and immunity · 2007Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Bordetella parapertussis and Bordetella pertussis are closely related species that cause whooping cough, an acute, immunizing disease. Their coexistence in the same host populations at the same time and vaccine studies showing that B. pertussis vaccines have little effect on B. parapertussis infection or disease suggest that the protective immunity induced by each does not efficiently cross protect against the other. Although the mechanisms of protective immunity to B. pertussis have been well studied, those of B. parapertussis have not. The present study explores the mechanism by which B. parapertussis is cleared from the lower respiratory tract by anamnestic immunity. Serum antibodies are necessary and sufficient for elimination of this bacterium, and CD4(+) T cells, complement, and neutrophils are required for serum antibody-mediated clearance. Mice lacking immunoglobulin A had no defect in their ability to control or clear infection. Interestingly, serum antibody-mediated clearance of B. parapertussis did not require Fc receptors that are required for antibody-mediated clearance of B. pertussis. Together these data support a model for the mechanism of protective immunity to B. parapertussis that is similar but distinct from that of B. pertussis.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.