Evidence map›Paper›PMID 16175512›Full record

ArticleAmerican journal of human genetics2005

Linkage disequilibrium mapping of quantitative-trait Loci by selective genotyping.

Zehua Chen, Gang Zheng, Kaushik Ghosh, Zhaohai Li

Abstract read
In one paragraph

Article in American journal of human genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Integrative analysis of genome-wide association studies and gene expression profiles identified candidate genes for osteoporosis in Kashin-Beck disease patients.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2016
    Article
  5. Article
  6. Analysis of Sequence Data Under Multivariate Trait-Dependent Sampling.Journal of the American Statistical Association · 2015
    Article
  7. Article
  8. Article
  9. Quantitative trait analysis in sequencing studies under trait-dependent sampling.Proceedings of the National Academy of Sciences of the United States of America · 2013
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Zehua ChenDepartment of Statistics and Applied Probability, National University of Singapore, Republic of Singapore. stachenz@nus.edu.sg
Gang Zheng
Kaushik Ghosh
Zhaohai Li

Funding

Statistical Methods for Genetic Study Design &AnalysisR01EY014478 · NEI · GEORGE WASHINGTON UNIVERSITY · PI LI, ZHAOHAI · 2002 to 2005
$701k
NEI NIH HHS EY014478NEI NIH HHS R01 EY014478
6 · The paper itself

Abstract

The principles of linkage disequilibrium mapping of dichotomous diseases can be well applied to the mapping of quantitative-trait loci through the method of selective genotyping. In 1999, M. Slatkin considered a truncation selection (TS) approach. We propose in this report an extended TS approach and an extreme-rank-selection (ERS) approach. The properties of these selection approaches are studied analytically. By using a simulation study, we demonstrate that both the extended TS approach and the ERS approach provide remarkable improvements over Slatkin's original TS approach.

Indexed as

Linkage DisequilibriumQuantitative Trait LociGenotypeHumans

Identifiers

PMID16175512
PMCPMC1275615

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.