Evidence map›Paper›PMID 16174927›Full record

ReviewNeurocritical care2004

Brain tissue salvage in acute stroke.

Perttu J Lindsberg

Abstract readReview
PubMed Publisher
In one paragraph

Review in Neurocritical care, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 3 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Perttu J LindsbergDepartment of Neurology, Helsinki University Central Hospital, Helsinki. perttu.lindsberg@hus.fi
Helsinki University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thrombolysis is the only effective medical therapy of ultra-acute (<3 hours) cerebral ischemia, and it is moving from academic centers to community-based standard therapy in experienced centers. Despite intensive experimental and clinical research, the salvage of brain cells through a host of neuroprotective strategies has not been demonstrated to be efficient. As the imaging and other patient selection methods continue to develop, it may be possible eventually to identify patients who still have viable penumbral brain tissue even after the 3-h window. This review focuses on the possibilities of salvaging acutely ischemic brain tissue and potential reasons for differences in the efficacies of the thrombolytic and neuroprotective therapies.

Indexed as

Thrombolytic TherapyBrain IschemiaHumansNeuroprotective AgentsStrokeTissue SurvivalNeuroprotective Agents

Identifiers

PMID16174927
OpenAlexW2019296423

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.