ArticleMolecular biology reports2005
Cloning, expression and characterization of the human NOB1 gene.
Article in Molecular biology reports, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Prognostic value of NOB1 expression levels in various cancers: a systematic review and meta-analysis.Biomarkers in medicine · 2024Pooled it
- Role of microRNA-363 during tumor progression and invasion.Journal of physiology and biochemistry · 2024Review
- Domain definition and preliminary functional exploration of the endonuclease NOBP-1 in Strongyloides stercoralis.Parasites & vectors · 2023Article
- Signal Pathways and microRNAs in Osteosarcoma Growth and the Dual Role of Mesenchymal Stem Cells in Oncogenesis.International journal of molecular sciences · 2023Review
- miRNA-612 suppresses ovarian cancer cell tumorigenicity by downregulating NOB1.American journal of translational research · 2022Article
- MicroRNA-363-3p downregulation in papillary thyroid cancer inhibits tumor progression by targeting NOB1.Journal of investigative medicine : the official publication of the American Federation for Clinical Research · 2021Article
- MiR-363 suppresses cell migration, invasion, and epithelial-mesenchymal transition of osteosarcoma by binding to NOB1.World journal of surgical oncology · 2020Observational
- RIG-I Has a Role in Immunity AgainstFrontiers in immunology · 2020Article
- [Eukaryotic translation elongation factor 1A1 positively regulates NOB1 expression to promote invasion and metastasis of hepatocellular carcinoma cellsNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2018Article
- Effects of NOB1 on the pathogenesis of osteosarcoma and its expression on the chemosensitivity to cisplatin.Oncology letters · 2018Article
- Evaluation of NIN/RPN12 binding protein inhibits proliferation and growth in human renal cancer cells.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015Article
- NOB1 is essential for the survival of RKO colorectal cancer cells.World journal of gastroenterology · 2015Article
- Knockdown of NOB1 expression inhibits the malignant transformation of human prostate cancer cells.Molecular and cellular biochemistry · 2014Article
- Downregulated miR-646 in clear cell renal carcinoma correlated with tumour metastasis by targeting the nin one binding protein (NOB1).British journal of cancer · 2014Article
- Nin one binding protein expression as a prognostic marker in prostate carcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2014Article
- NOB1 in non-small-cell lung cancer: expression profile and clinical significance.Pathology oncology research : POR · 2014Article
- Expression and clinical significance of the nin one binding protein and p38 MAPK in prostate carcinoma.International journal of clinical and experimental pathology · 2013Article
- Clinical significance of NOB1 expression in breast infiltrating ductal carcinoma.International journal of clinical and experimental pathology · 2013Article
- MicroRNA-326 functions as a tumor suppressor in glioma by targeting the Nin one binding protein (NOB1).PloS one · 2013Article
- Downregulation of NIN/RPN12 binding protein inhibit the growth of human hepatocellular carcinoma cells.Molecular biology reports · 2012Article
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The yeast Nob1p (Nin one binding protein) gene is required for proteasome function and RNA metabolism. We report here the cloning and characterization of the human orthologue NOB1 gene and its products. The human NOB1 gene is composed of nine exons and eight introns and is localized on human chromosome 16q22.1. The NOB1 cDNA is 1749 bp long and contains a putative open reading frame of 1239 bp. The predicted NOB1 protein comprises a PIN (PilT amino terminus) domain and a zinc ribbon domain. Western blot analysis showed that the molecular weight of NOB1 is about 50 KDa. RT-PCR analysis of mRNA from human adult tissues showed that NOB1 is expressed mainly in liver, lung and spleen. Expression of NOB1 in mammalian culture cells indicated that the NOB1 protein is mainly localized in the nucleus. Our data provides important information for further study of the function of the NOB1 gene and its products.
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