ArticleGenetics2006
Fine mapping and physical characterization of two linked quantitative trait loci affecting milk fat yield in dairy cattle on BTA26.
Article in Genetics, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Use of multivariate factor analysis of detailed milk fatty acid profile to perform a genome-wide association study in Italian Simmental and Italian Holstein.Journal of applied genetics · 2020Article
- Variation in the stearoyl-CoA desaturase gene (Archives animal breeding · 2020Article
- A novel selection signature in stearoyl-coenzyme A desaturase (SCD) gene for enhanced milk fat content in Bubalus bubalis.Tropical animal health and production · 2016Article
- Meuwissen et al. on Genomic Selection.Genetics · 2016Article
- Identification of Single Nucleotide Polymorphism Marker and Association Analysis of Marbling Score in Fas Gene of Hanwoo.Asian-Australasian journal of animal sciences · 2016Article
- Genome wide CNV analysis reveals additional variants associated with milk production traits in Holsteins.BMC genomics · 2014Article
- Genetic effects of stearoyl-coenzyme A desaturase (SCD) polymorphism on milk production traits in the Chinese dairy population.Molecular biology reports · 2012Article
- Mapping of a milk production quantitative trait locus to a 1.056 Mb region on bovine chromosome 5 in the Fleckvieh dual purpose cattle breed.Genetics, selection, evolution : GSE · 2011Article
- Mapping 49 quantitative trait loci at high resolution through sequencing-based genotyping of rice recombinant inbred lines.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2011Article
- Linear models for joint association and linkage QTL mapping.Genetics, selection, evolution : GSE · 2009Article
- Mapping genes for complex traits in domestic animals and their use in breeding programmes.Nature reviews. Genetics · 2009Review
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8 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Previously, a highly significant QTL affecting fat yield and protein yield and mapped to the bovine BTA26 chromosome has been reported to segregate in the French Holstein cattle population. To confirm and refine the location of this QTL, the original detection experiment was extended by adding 12 new families and genotyping 25 additional microsatellite markers (including 11 newly developed markers). Data were then analyzed by an approach combining both linkage and linkage disequilibrium information, making it possible to identify two linked QTL separated by 20 cM corresponding to approximately 29 Mb. The presence of a QTL affecting protein yield was confirmed but its position was found to be more telomeric than the two QTLunderlying fat yield. Each identified QTL affecting milk fat yield was physically mapped within a segment estimated to be <500 kb. Two strong functional candidate genes involved, respectively, in fatty acid metabolism and membrane permeability were found to be localized within this segment while other functional candidate genes were discarded. A haplotype comprising the favorable allele at each QTL position appears to be overrepresented in the artificial insemination bull population.
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