Evidence map›Paper›PMID 1617222›Full record

ArticleMammalian genome : official journal of the International Mammalian Genome Society1992

Organization and chromosomal locations of Rap1a/Krev sequences in the mouse.

N A Dower, M F Seldin, S Pugh, J C Stone

Abstract read
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In one paragraph

Article in Mammalian genome : official journal of the International Mammalian Genome Society, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Twelve genes, including the unassigned proteasome zeta subunit gene, ordered within the human 1p13 region.Mammalian genome : official journal of the International Mammalian Genome Society · 1998
    Article
  3. Article
  4. Typing recombinant inbred mouse strains for microsatellite markers on chromosomes 10, 16, 18, 19, and X.Mammalian genome : official journal of the International Mammalian Genome Society · 1995
    Article
  5. Linkage mapping of alpha-2 adrenergic receptor genes to mouse chromosomes 2 and 5.Mammalian genome : official journal of the International Mammalian Genome Society · 1993
    Article
  6. Mouse chromosome 3.Mammalian genome : official journal of the International Mammalian Genome Society · 1992
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

N A DowerDepartment of Paediatrics, University of Alberta, Edmonton, Canada.
M F Seldin
S Pugh
J C Stone
University of Alberta · CADuke University · USMassachusetts General Hospital · US

Funding

GENETICS OF RASR01CA048012 · NCI · JACKSON LABORATORY · PI STONE, JAMES C · 1988 to 1989
–
NCI NIH HHS CA48012NHGRI NIH HHS HG-00101
6 · The paper itself

Abstract

The human RAP1A gene encodes a protein that apparently can antagonize the function of oncogenic ras genes in gene transfer experiments, but its normal function is unknown. To understand the function of this gene, we have undertaken a study of the mouse homolog, Rap1a. The complete coding sequence of a mouse Rap1a cDNA has been determined, and genomic clones representing three distinct Rap1a species were recovered. We find that Rap1a is located on distal mouse Chromosome (Chr) 3 near Nras, Ampd-1, Tshb, Ngfb, and Atp1a1. Two related sequences (Rap1a-rs1 and Rap1a-rs2) were also characterized. Rap1a-rs1, which was not localized, has a sequence very similar to the Rap1a cDNA, suggesting that it has been recently acquired by the mouse genome. Rap1a-rs2 is more distantly related to the gene sequence and is located on Chr 2 near Actc-1.

Indexed as

Chromosome MappingAmino Acid SequenceAnimalsBase SequenceCloning, MolecularCrosses, GeneticDNAGTP-Binding ProteinsHumansImmunoblottingMiceMice, Inbred C3HMolecular Sequence Datarap GTP-Binding ProteinsRestriction MappingDNAGTP-Binding Proteinsrap GTP-Binding Proteins

Identifiers

PMID1617222
OpenAlexW2058065739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.