ArticleBreast cancer research : BCR2005
Overdiagnosis and overtreatment of breast cancer: overdiagnosis in randomised controlled trials of breast cancer screening.
Article in Breast cancer research : BCR, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 86 citations in OpenAlex.
- Screening for breast cancer: an update for the U.S. Preventive Services Task Force.Annals of internal medicine · 2009Pooled it
- Twenty five year follow-up for breast cancer incidence and mortality of the Canadian National Breast Screening Study: randomised screening trial.BMJ (Clinical research ed.) · 2014Trial
- Modelling the overdiagnosis of breast cancer due to mammography screening in women aged 40 to 49 in the United Kingdom.Breast cancer research : BCR · 2012Trial
- Rate of over-diagnosis of breast cancer 15 years after end of Malmö mammographic screening trial: follow-up study.BMJ (Clinical research ed.) · 2006Trial
- Overdetection of Breast Cancer.Current oncology (Toronto, Ont.) · 2022Article
- Article
- Article
- Overdiagnosis in the population-based organized breast cancer screening program estimated by a non-homogeneous multi-state model: a cohort study using individual data with long-term follow-up.Breast cancer research : BCR · 2018Article
- DNA methylation signature (SAM40) identifies subgroups of the Luminal A breast cancer samples with distinct survival.Oncotarget · 2017Article
- Mammography screening in three Finnish residential areas: comprehensive population-based study of breast cancer incidence and incidence-based mortality 1976-2009.British journal of cancer · 2015Article
- Overdiagnosis: epidemiologic concepts and estimation.Epidemiology and health · 2015Article
- Cost-effectiveness of MRI for breast cancer screening in BRCA1/2 mutation carriers.BMC cancer · 2013Article
- The benefits and harms of breast cancer screening: an independent review.British journal of cancer · 2013Review
- Overdiagnosis in breast cancer screening: the importance of length of observation period and lead time.Breast cancer research : BCR · 2013Article
- Overdiagnosis in screening mammography in Denmark: population based cohort study.BMJ (Clinical research ed.) · 2013Article
- Overdiagnosis from non-progressive cancer detected by screening mammography: stochastic simulation study with calibration to population based registry data.BMJ (Clinical research ed.) · 2011Article
- Breast cancer screening with mammography.Current oncology reports · 2011Review
- Interpreting overdiagnosis estimates in population-based mammography screening.Epidemiologic reviews · 2011Review
- Breast and other cancer dormancy as a therapeutic endpoint: speculative recombinant T cell receptor ligand (RTL) adjuvant therapy worth considering?BMC cancer · 2010Article
- Are UK cancer cure rates worse than in most other European countries?The British journal of general practice : the journal of the Royal College of General Practitioners · 2010Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Data from randomised controlled trials of mammographic screening can be used to determine the extent of any overdiagnosis, as soon as either a time equivalent to the lead-time has elapsed after the final screen, or the control arm has been offered screening. This paper reviews those randomised trials for which breast cancer incidence data are available. In recent trials in which the control group has not been offered screening, an excess incidence of breast cancer remains after many years of follow-up. In those trials in which the control arm has been offered screening, although there is a possible shift from invasive to in situ disease, there is no evidence of overdiagnosis as a result of incident screens.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.