Trial reportClinical oral investigations2005
A 2-year clinical evaluation of sealed noncavitated approximal posterior carious lesions in adolescents.
Trial report in Clinical oral investigations, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02338180 (A Randomized Clinical Trial on Preventive and Therapeutic Proximal Sealants), which is not on this map. Cited by 19 papers, 6 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
A Randomized Clinical Trial on Preventive and Therapeutic Proximal Sealants
Who cites it
19 citing papers in PubMed, 6 syntheses or guidelines pooled it, 80 citations in OpenAlex.
- Infiltration and sealing for managing non-cavitated proximal lesions: a systematic review and meta-analysis.BMC oral health · 2021Pooled it
- How to intervene in the caries process: proximal caries in adolescents and adults-a systematic review and meta-analysis.Clinical oral investigations · 2020Pooled it
- Nonrestorative Treatments for Caries: Systematic Review and Network Meta-analysis.Journal of dental research · 2019Pooled it
- Micro-invasive interventions for managing non-cavitated proximal caries of different depths: a systematic review and meta-analysis.Clinical oral investigations · 2018Pooled it
- A clinical guideline for caries infiltration of proximal enamel lesions with resins.British dental journal · 2018Guideline
- Micro-invasive interventions for managing proximal dental decay in primary and permanent teeth.The Cochrane database of systematic reviews · 2015Pooled it
- Efficacy of resin infiltration of proximal caries in primary molars: 1-year follow-up of a split-mouth randomized controlled clinical trial.Clinical oral investigations · 2018Trial
- The investigation of non-invasive techniques for treating early approximal carious lesions: an in vivo study.International dental journal · 2014Trial
- Sealing proximal surfaces with polyurethane tape: three-year evaluation.Clinical oral investigations · 2011Trial
- A two-year evaluation of four different fissure sealants.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2010Trial
- Comparative Assessment of Compomers and Ormocers as Pit and Fissure Sealants in Permanent Molars among Children Aged 7-9 Years.International journal of clinical pediatric dentistry · 2024Article
- Resin Infiltration of Non-Cavitated Enamel Lesions in Paediatric Dentistry: A Narrative Review.Children (Basel, Switzerland) · 2022Review
- Effect of resin infiltration application on early proximal caries lesions in vitro.Journal of dental sciences · 2021Article
- Tridimensional surface roughness analysis after resin infiltration of (deproteinized) natural subsurface carious lesions.Clinical oral investigations · 2015Article
- Efficacy of sealing the mesial surfaces of first permanent molars with respect to the status of the distal surfaces of the second primary molars in children at high caries-risk.European archives of paediatric dentistry : official journal of the European Academy of Paediatric Dentistry · 2014Article
- Influence of dental materials used for sealing caries lesions on laser fluorescence measurements.Lasers in medical science · 2012Article
- Progression of non-cavitated lesions in dentin through a nonsurgical approach: a preliminary 12-month clinical observation.European journal of dentistry · 2012Article
- Caries status and proximal lesion behaviour during a 6-year period in young adult Danes: an epidemiological investigation.Clinical oral investigations · 2010Article
- The effect of fluoride varnish and chlorhexidine gel on white spots and gingival and plaque indices in fixed orthodontic patients: A placebo-controlled study.Dental research journalArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The objective was to evaluate the clinical performance of a therapeutic sealant to arrest the progression of noncavitated approximal posterior carious lesions. The study population comprised 50 adolescents in whom bitewing radiographs had been taken for diagnosis of caries. Approximal noncavitated lesions in premolars and molars (4d-7m) were selected. One group (n=17) had a sealant placed after tooth separation on all enamel lesions. A second group (n=7) received sealant and fluoride varnish in a split-mouth design. A control group (n=26) received a standard fluoride varnish treatment without tooth separation. Follow-up radiographs were taken after 2 years and were analyzed together with the baseline radiographs in a blind study setting. About 93% of the sealed initial carious lesions showed no progression. The corresponding value for the fluoride varnish control group was 88%. In the split-mouth study, 92 and 88% of the surfaces with enamel caries showed no progression after sealant or fluoride varnish treatment, respectively. The difference between the two treatment procedures was not statistically significant. The incidence rate for the transition from enamel caries to dentin caries or fillings was 3.5-3.9 surfaces/100 years in the sealant groups and 5.9-6.1 surfaces/100 years in the fluoride varnish groups. The results show the potential of sealants to act as a noninvasive treatment of early approximal enamel lesions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.