ArticleJournal of autism and developmental disorders2005
Brief report: autism in individuals with Down syndrome.
Article in Journal of autism and developmental disorders, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Autism and Down syndrome: early identification and diagnosis.Arquivos de neuro-psiquiatria · 2022Pooled it
- Behavior in children with Down syndrome.Indian journal of pediatrics · 2008Trial
- Alternative Diagnoses in the Work Up of Down Syndrome Regression Disorder.Journal of autism and developmental disorders · 2025Article
- Autism Spectrum Disorder in Down Syndrome: Experiences from Caregivers.Journal of autism and developmental disorders · 2024Article
- Shared Etiology in Autism Spectrum Disorder and Epilepsy with Functional Disability.Behavioural neurology · 2022Review
- Autism spectrum disorder and epilepsy: Disorders with a shared biology.Epilepsy & behavior : E&B · 2015Review
- Autism in fragile X syndrome: a category mistake?Journal of the American Academy of Child and Adolescent Psychiatry · 2010Article
- Clinical report: a male with Down syndrome, fragile X syndrome, and autism.Journal of developmental and behavioral pediatrics : JDBP · 2010Article
- The role of the neurobiologist in redefining the diagnosis of autism.Brain pathology (Zurich, Switzerland) · 2007Review
- Diagnosing Autism in Individuals with Known Genetic Syndromes: Clinical Considerations and Implications for Intervention.International review of research in developmental disabilitiesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
As an off-shoot of a study examining the reliability and validity of an adapted version of the Pre-Linguistic Autism Diagnostic Observation Schedule (A-PL-ADOS), 13 individuals with Down syndrome with IQs ranging between 24 and 48 were administered the Autism Diagnostic Interview-Revised (ADI-R) and the A-PL-ADOS, which are well-validated interview and observational diagnostic measures. Three out of 13 met lifetime criteria on the ADI-R, but none of these three showed behavior that met the criterion for autism on the A-PL-ADOS (although two nearly did so). However, two individuals did meet the A-PL-ADOS criterion and showed behavior that fell only just short of meeting lifetime criteria on the ADI-R. Altogether, 5 individuals with Down syndrome may be considered to show an autism spectrum disorder. Of the remaining 8, some showed a few autistic features, and some showed none. The findings raise both methodological and conceptual issues.
Indexed as
Identifiers
16167094What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.