ArticleJournal of bacteriology2005
Control of the expression and compartmentalization of (sigma)G activity during sporulation of Bacillus subtilis by regulators of (sigma)F and (sigma)E.
Article in Journal of bacteriology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 26 citations in OpenAlex.
- Acetylation of the histone-like protein HBsu at specific sites alters gene expression during sporulation inFrontiers in microbiology · 2025Article
- Structural Analysis ofMicroorganisms · 2023Article
- Proteases HtrA and HtrB for α-amylase secreted from Bacillus subtilis in secretion stress.Cell stress & chaperones · 2019Review
- SpoVT: From Fine-Tuning Regulator inFrontiers in microbiology · 2016Article
- Antimicrobial copper alloy surfaces are effective against vegetative but not sporulated cells of gram-positive Bacillus subtilis.MicrobiologyOpen · 2015Article
- The Clostridium sporulation programs: diversity and preservation of endospore differentiation.Microbiology and molecular biology reviews : MMBR · 2015Review
- σK of Clostridium acetobutylicum is the first known sporulation-specific sigma factor with two developmentally separated roles, one early and one late in sporulation.Journal of bacteriology · 2014Article
- Global analysis of the sporulation pathway of Clostridium difficile.PLoS genetics · 2013Article
- Coupling of σG activation to completion of engulfment during sporulation of Bacillus subtilis survives large perturbations to DNA translocation and replication.Journal of bacteriology · 2012Article
- Pleiotropic functions of catabolite control protein CcpA in Butanol-producing Clostridium acetobutylicum.BMC genomics · 2012Article
- Dynamic expression of the translational machinery during Bacillus subtilis life cycle at a single cell level.PloS one · 2012Article
- Recent progress in Bacillus subtilis sporulation.FEMS microbiology reviews · 2012Review
- Loss of compartmentalization of σ(E) activity need not prevent formation of spores by Bacillus subtilis.Journal of bacteriology · 2010Article
- A feeding tube model for activation of a cell-specific transcription factor during sporulation in Bacillus subtilis.Genes & development · 2009Article
- Processing of a membrane protein required for cell-to-cell signaling during endospore formation in Bacillus subtilis.Journal of bacteriology · 2008Article
- A novel pathway of intercellular signalling in Bacillus subtilis involves a protein with similarity to a component of type III secretion channels.Molecular microbiology · 2008Article
- The transcriptional program underlying the physiology of clostridial sporulation.Genome biology · 2008Article
- Expression of the sigmaF-directed csfB locus prevents premature appearance of sigmaG activity during sporulation of Bacillus subtilis.Journal of bacteriology · 2007Article
- Separation of chromosome termini during sporulation of Bacillus subtilis depends on SpoIIIE.Journal of bacteriology · 2007Article
- Blocking chromosome translocation during sporulation of Bacillus subtilis can result in prespore-specific activation of sigmaG that is independent of sigmaE and of engulfment.Journal of bacteriology · 2006Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
During formation of spores by Bacillus subtilis the RNA polymerase factor sigma(G) ordinarily becomes active during spore formation exclusively in the prespore upon completion of engulfment of the prespore by the mother cell. Formation and activation of sigma(G) ordinarily requires prior activity of sigma(F) in the prespore and sigma(E) in the mother cell. Here we report that in spoIIA mutants lacking both sigma(F) and the anti-sigma factor SpoIIAB and in which sigma(E) is not active, sigma(G) nevertheless becomes active. Further, its activity is largely confined to the mother cell. Thus, there is a switch in the location of sigma(G) activity from prespore to mother cell. Factors contributing to the mother cell location are inferred to be read-through of spoIIIG, the structural gene for sigma(G), from the upstream spoIIG locus and the absence of SpoIIAB, which can act in the mother cell as an anti-sigma factor to sigma(G). When the spoIIIG locus was moved away from spoIIG to the distal amyE locus, sigma(G) became active earlier in sporulation in spoIIA deletion mutants, and the sporulation septum was not formed, suggesting that premature sigma(G) activation can block septum formation. We report a previously unrecognized control in which SpoIIGA can prevent the appearance of sigma(G) activity, and pro-sigma(E) (but not sigma(E)) can counteract this effect of SpoIIGA. We find that in strains lacking sigma(F) and SpoIIAB and engineered to produce active sigma(E) in the mother cell without the need for SpoIIGA, sigma(G) also becomes active in the mother cell.
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