ArticleJournal of bacteriology2005
Revisiting the evolution of Mycobacterium bovis.
Article in Journal of bacteriology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prevalence of bovine tuberculosis in dairy cattle in China during 2010-2019: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2021Pooled it
- Bovine Tuberculosis in Raw Milk: A Herd-Level Prevalence Study by PCR and ELISA Testing in Sylhet Region of Bangladesh.Veterinary medicine and science · 2026Article
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- Global-scale GWAS associates a subset of SNPs with animal-adapted variants in M. tuberculosis complex.BMC medical genomics · 2023Article
- Mapping the phylogeny and lineage history of geographically distinct BCG vaccine strains.Microbial genomics · 2023Article
- Specific identification ofMethodsX · 2023Article
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- Monocytic myeloid-derived suppressor cells reflect tuberculosis severity and are influenced by cyclooxygenase-2 inhibitors.Journal of leukocyte biology · 2021Article
- Complete Genome Sequence of Mycobacterium orygis Strain 51145.Microbiology resource announcements · 2021Article
- An African origin forEvolution, medicine, and public health · 2020Article
- RskA Is a Dual Function Activator-Inhibitor That Controls SigK Activity Across Distinct Bacterial Genera.Frontiers in microbiology · 2020Article
- Isolation and Immunological Detection ofEthiopian journal of health sciences · 2020Article
- RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection.PLoS pathogens · 2018Article
- A New Phylogenetic Framework for the Animal-AdaptedFrontiers in microbiology · 2018Article
- Breaking Transmission with Vaccines: The Case of Tuberculosis.Microbiology spectrum · 2017Review
- Patterns and processes of Mycobacterium bovis evolution revealed by phylogenomic analyses.Genome biology and evolution · 2017Article
- Pulmonary tuberculosis caused by Mycobacterium bovis in China.Scientific reports · 2015Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Though careful consideration has been placed towards genetic characterization of tubercle bacillus isolates causing disease in humans, those causing disease predominantly among wild and domesticated mammals have received less attention. In contrast to Mycobacterium tuberculosis, whose host range is largely specific to humans, M. bovis and "M bovis-like" organisms infect a broad range of animal species beyond their most prominent host in cattle. To determine whether strains of variable genomic content are associated with distinct distributions of disease, the DNA contents of M. bovis or M. bovis-like isolates from a variety of hosts were investigated via Affymetrix GeneChip. Consistent with previous genomic analysis of the M. tuberculosis complex (MTC), large sequence polymorphisms of putative diagnostic and biological consequence were able to unambiguously distinguish interrogated isolates. The distribution of deleted regions indicates organisms genomically removed from M. bovis and also points to structured genomic variability within M. bovis. Certain genomic profiles spanned a variety of hosts but were clustered by geography, while others associated primarily with host type. In contrast to the prevailing assumption that M. bovis has broad host capacity, genomic profiles suggest that distinct MTC lineages differentially infect a variety of mammals. From this, a phylogenetic stratification of genotypes offers a predictive framework upon which to base future genetic and phenotypic studies of the MTC.
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