ArticleGenetics2005
Equilibrium processes cannot explain high levels of short- and medium-range linkage disequilibrium in the domesticated grass Sorghum bicolor.
Article in Genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis identifies pleiotropic loci controlling phenotypic trade-offs in sorghum.Genetics · 2021Pooled it
- Genome-wide association study identifies consistent genomic loci for yield and nutritional quality in Ethiopian sorghum landraces.The plant genome · 2026Article
- Recent advances in breeding systems and their improvement in forage crops.Molecular biology reports · 2025Review
- Multi-locus genome-wide association mapping for major agronomic and yield-related traits in sorghum (Sorghum bicolor (L.) moench) landraces.BMC genomics · 2025Article
- Unveiling the Potential Role of Dhurrin in Sorghum During Infection by the Head Smut PathogenPlants (Basel, Switzerland) · 2025Article
- Identifying genetic determinants of forage sorghum [Sorghum bicolor (Moench)] adaptation through GWAS.BMC plant biology · 2024Article
- Genetic diversity, population structure, and a genome-wide association study of sorghum lines assembled for breeding in Uganda.Frontiers in plant science · 2024Article
- Genome-wide association study reveals genomic loci influencing agronomic traits in Ethiopian sorghum (Molecular breeding : new strategies in plant improvement · 2023Article
- A genomics resource for genetics, physiology, and breeding of West African sorghum.The plant genome · 2021Article
- The Road to Sorghum Domestication: Evidence From Nucleotide Diversity and Gene Expression Patterns.Frontiers in plant science · 2021Article
- Comparative population genomics reveals genetic divergence and selection in lotus, Nelumbo nucifera.BMC genomics · 2020Article
- Genomic signatures of adaptation to Sahelian and Soudanian climates in sorghum landraces of Senegal.Ecology and evolution · 2019Article
- An Integrated Genotyping-by-Sequencing Polymorphism Map for Over 10,000 Sorghum Genotypes.The plant genome · 2019Article
- The Sorghum QTL Atlas: a powerful tool for trait dissection, comparative genomics and crop improvement.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Semiautomated Feature Extraction from RGB Images for Sorghum Panicle Architecture GWAS.Plant physiology · 2019Article
- Genetic architecture of photosynthesis in Sorghum bicolor under non-stress and cold stress conditions.Journal of experimental botany · 2017Article
- Sub-genomic selection patterns as a signature of breeding in the allopolyploid Brassica napus genome.BMC genomics · 2014Article
- Association mapping of brassinosteroid candidate genes and plant architecture in a diverse panel of Sorghum bicolor.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2014Article
- Article
- Association mapping provides insights into the origin and the fine structure of the sorghum aluminum tolerance locus, AltSB.PloS one · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patterns of linkage disequilibrium (LD) are of interest because they provide evidence of both equilibrium (e.g., mating system or long-term population structure) and nonequilibrium (e.g., demographic or selective) processes, as well as because of their importance in strategies for identifying the genetic basis of complex phenotypes. We report patterns of short and medium range (up to 100 kb) LD in six unlinked genomic regions in the partially selfing domesticated grass, Sorghum bicolor. The extent of allelic associations in S. bicolor, as assessed by pairwise measures of LD, is higher than in maize but lower than in Arabidopsis, in qualitative agreement with expectations based on mating system. Quantitative analyses of the population recombination parameter, rho, however, based on empirical estimates of rates of recombination, mutation, and self-pollination, show that LD is more extensive than expected under a neutral equilibrium model. The disparity between rho and the population mutation parameter, , is similar to that observed in other species whose population history appears to be complex. From a practical standpoint, these results suggest that S. bicolor is well suited for association studies using reasonable numbers of markers, since LD typically extends at least several kilobases but has largely decayed by 15 kb.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.