ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2005
Health-related quality of life in preschool children with wheezing and dyspnea: preliminary results from a random general population sample.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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6 citing papers in PubMed, 32 citations in OpenAlex.
- Relation of Asthma Control with Quality of Life among a Sample of Egyptian Asthmatic School Children.Open access Macedonian journal of medical sciences · 2019Article
- Association between maternal smoking during pregnancy and recurrent wheezing in infancy: evidence from a meta-analysis.International journal of clinical and experimental medicine · 2015Article
- Health-related quality of life of infants from ethnic minority groups: the Generation R Study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2013Article
- Asthma-like symptoms in the first year of life and health-related quality of life at age 12 months: the Generation R study.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2012Article
- Health-related quality of life of "left-behind children": a cross-sectional survey in rural China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2010Article
- Reliability and validity of the Infant and Toddler Quality of Life Questionnaire (ITQOL) in a general population and respiratory disease sample.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2007Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
Respiratory symptoms have a high prevalence among preschool children (5-20%). This study evaluated the impact of parent-reported respiratory symptoms on health-related quality of life (HRQOL) using the TNO-AZL Preschool Children Quality of Life (TAPQOL) questionnaire. A random general population sample of 500 parents of 3-46-month old children was mailed a questionnaire containing the TAPQOL and questions on the prevalence of respiratory symptoms. The impact of respiratory symptoms on HRQOL was analysed using the Mann-Whitney test and linear regression analysis. Response rate was 83%. The prevalence of combined "wheezing and dyspnea" during the past 4 weeks was 10%. For the sleeping, appetite, lung problems, skin problems, communication, and positive mood TAPQOL scales, HRQOL was significantly lower in the subgroup with "wheezing and dyspnea" (n = 41) than in the subgroup without symptoms (n = 321); large effect sizes were observed for lung problems (2.06) and sleeping (0.80). In multivariate analysis, adjusted for age and gender of the child, "wheezing and dyspnea" were associated with the scales sleeping, appetite, lung problems, communication, and positive mood (p < 0.05). In conclusion, decreases in HRQOL among preschoolers with parent-reported respiratory symptoms are measurable with the TAPQOL. We recommend studying the impact of doctor-diagnosed respiratory symptoms on HRQOL in future studies.
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