Evidence map›Paper›PMID 16155609›Full record

ReviewOncogene2005

Human T-cell leukemia/lymphoma virus type 1 nonstructural genes and their functions.

Christophe Nicot, Robert L Harrod, Vincenzo Ciminale, Genoveffa Franchini

Abstract readReview
PubMed Publisher
In one paragraph

Review in Oncogene, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Regulation of HTLV-1 transformation.Bioscience reports · 2022
    Review
  5. HTLV-1 activates YAP via NF-κB/p65 to promote oncogenesis.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  6. Article
  7. Tuning Rex rules HTLV-1 pathogenesis.Frontiers in immunology · 2022
    Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Oncogenes and RNA splicing of human tumor viruses.Emerging microbes & infections · 2014
    Review
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Christophe NicotDepartment of Microbiology, University of Kansas Medical Center, Molecular Genetics, and Immunology, 3025 Wahl Hall West, 3901 Rainbow Boulevard, Kansas City, KS 66160-7420, USA.
Robert L Harrod
Vincenzo Ciminale
Genoveffa Franchini

Funding

Mechanisms of human T-cell immortalization by HTLV-I TaxR01CA106258 · NCI · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NICOT, CHRISTOPHE P · 2005 to 2015
$2.2M
Regulation of HTLV-I replication by the viral p30R01AI058944 · NIAID · UNIVERSITY OF KANSAS MEDICAL CENTER · PI NICOT, CHRISTOPHE P · 2005 to 2009
$1.3M
NCI NIH HHS R01 CA106258NIAID NIH HHS R01 AI058944
6 · The paper itself

Abstract

The human T-cell leukemia/lymphoma virus (HTLV) genome, in addition to the structural Gag and Env proteins and retroviral enzymes, carries a region at its 3' end originally designated pX. To date, we know that this region encodes two essential transcriptional and post-transcriptional positive regulators of viral expression, the Tax and Rex proteins, respectively (reviewed elsewhere in this issue). Here, we will review current knowledge of the functions of three additional proteins encoded in the pX region, p12I, p13II, and p30II.

Indexed as

Amino Acid SequenceGenome, ViralHuman T-lymphotropic virus 1Models, BiologicalMolecular Sequence DataOpen Reading FramesRNA Processing, Post-TranscriptionalTranscription, GeneticViral Nonstructural ProteinsViral Nonstructural Proteins

Identifiers

PMID16155609

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.