ArticleMammalian genome : official journal of the International Mammalian Genome Society2005
A comprehensive SNP-based genetic analysis of inbred mouse strains.
Article in Mammalian genome : official journal of the International Mammalian Genome Society, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
31 citing papers in PubMed, 54 citations in OpenAlex.
- Substrain-specific behavioral variation in female C57BL/6 and C57BL/10 mice.Frontiers in behavioral neuroscience · 2026Article
- Comparative phenotyping of C57BL/6J substrains reveals distinctive patterns of cardiac aging.GeroScience · 2025Article
- Long-read RNA sequencing reveals allele-specificGenome research · 2025Article
- Multiplex Detection of SNPs for Genetic Monitoring in Laboratory Mice by Luminex xTAG Assay.Genes · 2024Article
- Long-read RNA sequencing reveals allele-specific NbioRxiv : the preprint server for biology · 2024Article
- Genetic association of nucleus accumbens 5-hydroxyindoleacetic acid level and alcohol preference drinking in a quasi-congenic male mice: Potential modulation byDrug and alcohol dependence reports · 2022Article
- Substrains matter in phenotyping of C57BL/6 mice.Experimental animals · 2021Review
- Whole Genome Sequencing of the Mutamouse Model Reveals Strain- and Colony-Level Variation, and Genomic Features of the Transgene Integration Site.Scientific reports · 2019Article
- A New Understanding of the Role of IL-1 in Age-Related Intervertebral Disc Degeneration in a Murine Model.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019Article
- Association of Nrf2 polymorphism haplotypes with acute lung injury phenotypes in inbred strains of mice.Antioxidants & redox signaling · 2015Article
- Validation of simple sequence length polymorphism regions of commonly used mouse strains for marker assisted speed congenics screening.International journal of genomics · 2015Article
- Development of SNP markers for C57BL/6N-derived mouse inbred strains.Experimental animals · 2015Article
- Identification of Ssm1b, a novel modifier of DNA methylation, and its expression during mouse embryogenesis.Development (Cambridge, England) · 2014Article
- Mouse cell line authentication.Cytotechnology · 2014Article
- Genomic structure and variation of nuclear factor (erythroid-derived 2)-like 2.Oxidative medicine and cellular longevity · 2013Review
- 1 + 1 = 3: Development and validation of a SNP-based algorithm to identify genetic contributions from three distinct inbred mouse strains.Journal of biomolecular techniques : JBT · 2012Article
- Analysis of Arabidopsis genome-wide variations before and after meiosis and meiotic recombination by resequencing Landsberg erecta and all four products of a single meiosis.Genome research · 2012Article
- From markers to molecular mechanisms: type 1 diabetes in the post-GWAS era.The review of diabetic studies : RDS · 2012Review
- The relevance of individual genetic background and its role in animal models of epilepsy.Epilepsy research · 2011Review
- Vesico-ureteric reflux: using mouse models to understand a common congenital urinary tract defect.Pediatric nephrology (Berlin, Germany) · 2011Article
Corrections and comments
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Authors and funding
11 authors at 3 institutions in 1 country.
Funding
Abstract
Dense genetic maps of mammalian genomes facilitate a variety of biological studies including the mapping of polygenic traits, positional cloning of monogenic traits, mapping of quantitative or qualitative trait loci, marker association, allelic imbalance, speed congenic construction, and evolutionary or phylogenetic comparison. In particular, single nucleotide polymorphisms (SNPs) have proved useful because of their abundance and compatibility with multiple high-throughput technology platforms. SNP genotyping is especially suited for the genetic analysis of model organisms such as the mouse because biallelic markers remain fully informative when used to characterize crosses between inbred strains. Here we report the mapping and genotyping of 673 SNPs (including 519 novel SNPs) in 55 of the most commonly used mouse strains. These data have allowed us to construct a phylogenetic tree that correlates and expands known genealogical relationships and clarifies the origin of strains previously having an uncertain ancestry. All 55 inbred strains are distinguishable genetically using this SNP panel. Our data reveal an uneven SNP distribution consistent with a mosaic pattern of inheritance and provide some insight into the changing dynamics of the physical architecture of the genome. Furthermore, these data represent a valuable resource for the selection of markers and the design of experiments that require the genetic distinction of any pair of mouse inbred strains such as the generation of congenic mice, positional cloning, and the mapping of quantitative or qualitative trait loci.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.