ArticleNucleic acids research1992
Zfp-37, a new murine zinc finger encoding gene, is expressed in a developmentally regulated pattern in the male germ line.
Article in Nucleic acids research, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Construction of a high-density genetic map and fine QTL mapping for growth and nutritional traits of Crassostrea gigas.BMC genomics · 2018Article
- The shorter zinc finger protein ZNF230 gene message is transcribed in fertile male testes and may be related to human spermatogenesis.The Biochemical journal · 2001Article
- An unexpected localization of basonuclin in the centrosome, mitochondria, and acrosome of developing spermatids.The Journal of cell biology · 1997Article
- Zfp-51, a murine zinc finger encoding gene mapping to the t-complex region of chromosome 17, encodes 19 contiguous zinc fingers and is ubiquitously expressed.Mammalian genome : official journal of the International Mammalian Genome Society · 1994Article
- A testis-specific gene encoding a nuclear high-mobility-group box protein located in elongating spermatids.Molecular and cellular biology · 1993Article
- New nucleotide sequence data on the EMBL File Server.Nucleic acids research · 1992Article
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Authors and funding
2 authors.
Funding
Abstract
To begin to examine the function in the mouse testis of genes containing the zinc finger motif, we have screened an adult mouse total testis cDNA library with probes to a conserved region of zinc fingers. We have isolated cDNAs for a new murine zinc finger encoding gene that has been designated Zfp-37. Northern blot hybridization analysis revealed Zfp-37 transcripts at high levels in the testis, the only adult tissue in which Zfp-37 expression was observed. Zfp-37 was also expressed at lower levels in the mid-gestation embryo and placenta. The major testicular transcripts are 2.3 and 2.6 kb. A 4.0 kb transcript was detected at lower levels in the testis as well as in embryo and placenta. Northern blot and in situ hybridization analysis revealed that expression of Zfp-37 was most abundant in germ cells which have completed meiosis and are undergoing the complex morphogenetic changes of spermiogenesis. The pattern of expression of Zfp-37 and the presence of the zinc finger domain suggest that Zfp-37 may have a role in regulating spermiogenesis.
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