Evidence map›Paper›PMID 16145166›Full record

ArticleJournal of clinical microbiology2005

Direct application of the INNO-LiPA Rif.TB line-probe assay for rapid identification of Mycobacterium tuberculosis complex strains and detection of rifampin resistance in 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis.

Miguel Viveiros, Clara Leandro, Liliana Rodrigues, Josefina Almeida, Rosário Bettencourt, Isabel Couto, Lurdes Carrilho, José Diogo, Ana Fonseca, Luís Lito and 7 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 69 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Molecular Diagnosis of Tuberculosis.Chonnam medical journal · 2018
    Review
  6. Prevalence of mutations in genes associated with rifampicin and isoniazid resistance inJournal of clinical tuberculosis and other mycobacterial diseases · 2017
    Article
  7. Article
  8. General and advanced diagnostic tools to detect Mycobacterium tuberculosis and their drug susceptibility: a review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2015
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. HIV-Associated Tuberculosis in the Newborn and Young Infant.International journal of pediatrics · 2011
    Article
  19. Use of the INNO LiPA Rif.TB for detection of Mycobacterium tuberculosis DNA directly in clinical specimens and for simultaneous determination of rifampin susceptibility.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2007
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 9 institutions in 2 countries.

Miguel ViveirosUnidade de Micobacterias do Instituto de Higiene e Medicina Tropical, Lisboa, Portugal.
Clara Leandro
Liliana Rodrigues
Josefina Almeida
Rosário Bettencourt
Isabel Couto
Lurdes Carrilho
José Diogo
Ana Fonseca
Luís Lito
João Lopes
Teresa Pacheco
Mariana Pessanha
Judite Quirim
Luísa Sancho
Max Salfinger
Leonard Amaral
Universidade Nova de Lisboa · PTHospital de Egas Moniz · PTHospital de Santa Maria · PTHospital de São Bernardo · PTHospital Garcia de Orta · PTHospital of St. Francis Xavier · PTHospital Prof. Dr. Fernando Fonseca · PTHospital Pulido Valente · PTNew York State Department of Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The INNO-LiPA Rif.TB assay for the identification of Mycobacterium tuberculosis complex strains and the detection of rifampin (RIF) resistance has been evaluated with 360 smear-positive respiratory specimens from an area of high incidence of multidrug-resistant tuberculosis (MDR-TB). The sensitivity when compared to conventional identification/culture methods was 82.2%, and the specificity was 66.7%; the sensitivity and specificity were 100.0% and 96.9%, respectively, for the detection of RIF resistance. This assay has the potential to provide rapid information that is essential for the effective management of MDR-TB.

Indexed as

Drug Resistance, BacterialAntibiotics, AntitubercularDNA-Directed RNA PolymerasesHumansIncidenceMicrobial Sensitivity TestsMycobacterium tuberculosisNucleic Acid HybridizationRifampinSputumTime FactorsTuberculosis, Multidrug-ResistantTuberculosis, PulmonaryAntibiotics, AntitubercularDNA-Directed RNA PolymerasesRifampinRNA polymerase beta subunit

Identifiers

PMID16145166
PMCPMC1234138
OpenAlexW2157620029

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.