ArticleGenetics2005
Quantitative trait loci for cuticular hydrocarbons associated with sexual isolation between Drosophila simulans and D. sechellia.
Article in Genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 67 citations in OpenAlex.
- Two major-effect loci influence interspecific mating in females of the sibling species, Drosophila simulans and D. sechellia.G3 (Bethesda, Md.) · 2025Article
- Review
- Identifying female phenotypes that promote behavioral isolation in a sexually dimorphic species of fishCurrent zoology · 2021Article
- The complex genetic architecture of male mate choice evolution between Drosophila species.Heredity · 2020Article
- Evolution of Reproductive Behavior.Genetics · 2020Review
- Calmodulin-binding transcription factor shapes the male courtship song in Drosophila.PLoS genetics · 2019Article
- Article
- Tissue-Specific cis-Regulatory Divergence Implicates eloF in Inhibiting Interspecies Mating in Drosophila.Current biology : CB · 2018Article
- The role of cuticular hydrocarbons in mate recognition in Drosophila suzukii.Scientific reports · 2018Article
- Genetic and Transgenic Reagents forG3 (Bethesda, Md.) · 2017Article
- Quantitative Trait Locus Analysis of Mating Behavior and Male Sex Pheromones in Nasonia Wasps.G3 (Bethesda, Md.) · 2016Article
- Genetic architecture of natural variation in cuticular hydrocarbon composition in Drosophila melanogaster.eLife · 2015Article
- Heritable variation in courtship patterns in Drosophila melanogaster.G3 (Bethesda, Md.) · 2015Article
- Premating isolation is determined by larval rearing substrates in cactophilic Drosophila mojavensis. X. Age-specific dynamics of adult epicuticular hydrocarbon expression in response to different host plants.Ecology and evolution · 2014Article
- No boundaries: genomes, organisms, and ecological interactions responsible for divergence and reproductive isolation.The Journal of heredity · 2014Review
- Interaction between temperature and male pheromone in sexual isolation in Drosophila melanogaster.Journal of evolutionary biology · 2013Article
- Behavioural reproductive isolation and speciation in Drosophila.Journal of biosciences · 2012Review
- The genetic basis of female mate preference and species isolation in Drosophila.International journal of evolutionary biology · 2012Article
- Identification, expression and target gene analyses of Micrornas in Spodoptera litura.PloS one · 2012Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The identification of genes with large effects on sexual isolation and speciation is an important link between classic evolutionary genetics and molecular biology. Few genes that affect sexual isolation and speciation have been identified, perhaps because many traits influencing sexual isolation are complex behaviors. Cuticular hydrocarbons (CHs) of species of the Drosophila melanogaster group play a large role in sexual isolation by functioning as contact pheromones influencing mate recognition. Some of the genes that play key roles in determining species-specific CHs have been identified. We have performed separate quantitative trait locus (QTL) analyses of 7-tricosene (7-T) and 7,11-heptacosadiene (7,11-HD), the two major female CHs differing between D. simulans and D. sechellia. We find that approximately 40% of the phenotypic variance in each CH is associated with two to four chromosomal regions. A region on the right arm of chromosome 3 contains QTL that affect both traits, but other QTL are in distinct chromosomal regions. Epistatic interactions were detected between two pairs of QTL for 7,11-HD such that if either were homozygous for the D. simulans allele, the fly was similar to D. simulans in phenotype, with a low level of 7,11-HD. We discuss the location of these regions with regard to candidate genes for CH production, including those for desaturases.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.