ArticleGenetics2005
Monitoring the mode and tempo of concerted evolution in the Drosophila melanogaster rDNA locus.
Article in Genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed.
- Copy number and sequence variation in ribosomal DNA and the transposon, Pokey, in mutation accumulation lines of Daphnia obtusa.G3 (Bethesda, Md.) · 2026Article
- Effect of copper and nickel exposure on ribosomal DNA variation in Daphnia pulex mutation accumulation lines.G3 (Bethesda, Md.) · 2025Article
- Under the magnifying glass: The ups and downs of rDNA copy number.Seminars in cell & developmental biology · 2023Review
- Varying strength of selection contributes to the intragenomic diversity of rRNA genes.Nature communications · 2022Article
- Transcribed sex-specific markers on the Y chromosome of the oriental fruit fly, Bactrocera dorsalis.BMC genetics · 2020Article
- The peculiar genetics of the ribosomal DNA blurs the boundaries of transgenerational epigenetic inheritance.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2019Review
- Genomic Copy-Number Loss Is Rescued by Self-Limiting Production of DNA Circles.Molecular cell · 2018Article
- Evolutionary trends in animal ribosomal DNA loci: introduction to a new online database.Chromosoma · 2018Article
- Evolutionary insight on localization of 18S, 28S rDNA genes on homologous chromosomes in Primates genomes.Comparative cytogenetics · 2018Article
- Unstable Inheritance of 45S rRNA Genes inG3 (Bethesda, Md.) · 2017Article
- Ribosomal RNA Genes Contribute to the Formation of Pseudogenes and Junk DNA in the Human Genome.Genome biology and evolution · 2017Article
- Distribution of the DNA transposon family, Pokey in the Daphnia pulex species complex.Mobile DNA · 2016Article
- Divergence thresholds and divergent biodiversity estimates: can metabarcoding reliably describe zooplankton communities?Ecology and evolution · 2015Article
- Integration, Regulation, and Long-Term Stability of R2 Retrotransposons.Microbiology spectrum · 2015Review
- Reduced rDNA copy number does not affect "competitive" chromosome pairing in XYY males of Drosophila melanogaster.G3 (Bethesda, Md.) · 2014Article
- Copy number of the transposon, Pokey, in rDNA is positively correlated with rDNA copy number in Daphnia obtuse [corrected].PloS one · 2014Article
- Article
- A population genetic model for the maintenance of R2 retrotransposons in rRNA gene loci.PLoS genetics · 2013Article
- Y chromosome mediates ribosomal DNA silencing and modulates the chromatin state in Drosophila.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Sequencing our way towards understanding global eukaryotic biodiversity.Trends in ecology & evolution · 2012Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Non-LTR retrotransposons R1 and R2 have persisted in rRNA gene loci (rDNA) since the origin of arthropods despite their continued elimination by the recombinational mechanisms of concerted evolution. This study evaluated the short-term evolutionary dynamics of the rDNA locus by measuring the divergence among replicate Drosophila melanogaster lines after 400 generations. The total number of rDNA units on the X chromosome of each line varied from 140 to 310, while the fraction of units inserted with R1 and R2 retrotransposons ranged from 37 to 65%. This level of variation is comparable to that found in natural population surveys. Variation in locus size and retrotransposon load was correlated with large changes in the number of uninserted and R1-inserted units, yet the numbers of R2-inserted units were relatively unchanged. Intergenic spacer (IGS) region length variants were also used to evaluate changes in the rDNA loci. All IGS length variants present in the lines showed significant increases and decreases of copy number. These studies, combined with previous data following specific R1 and R2 insertions in these lines, help to define the type and distribution, both within the locus and within the individual units, of recombinational events that give rise to the concerted evolution of the rDNA locus.
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Registered trials
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