Evidence map›Paper›PMID 16142990›Full record

GuidelineCNS drugs2005

Guide to anaesthetic selection for electroconvulsive therapy.

Klaus J Wagner, Oliver Möllenberg, Michael Rentrop, Christian Werner, Eberhard F Kochs

Registry-linked trialAbstract readGuidelinePractice GuidelineReview
PubMed Publisher
In one paragraph

Guideline in CNS drugs, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01441960 (Optimal Control of Muscle Strength for Electroconvulsive Therapy), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01441960 nacompletednot on this mapstarted 2011, after this paper: background citation

Optimal Control of Muscle Strength for Electroconvulsive Therapy: A Comparison of Succinylcholine Versus Rocuronium-induced Neuromuscular Blockade

TypeinterventionalSponsorMassachusetts General HospitalRan2011 to 2015Enrolled45ConditionsNeuromuscular Blockade, ECTArmsSuccinylcholine, Rocuronium
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 64 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Article
  7. Anesthetic care for electroconvulsive therapy.Anesthesia and pain medicine · 2022
    Review
  8. Article
  9. Article
  10. S -ketamine compared to etomidate during electroconvulsive therapy in major depression.European archives of psychiatry and clinical neuroscience · 2017
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Klaus J WagnerKlinik für Anaesthesiologie, Klinikum rechts der Isar, Technische Universität München, München, Germany. K.Wagner@lrz.tum.de
Oliver Möllenberg
Michael Rentrop
Christian Werner
Eberhard F Kochs
Technical University of Munich · DEKlinikum rechts der Isar · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Electroconvulsive therapy (ECT) is used in the treatment of severe psychiatric disorders. It involves the induction of a seizure for therapeutic purposes by the administration of a variable-frequency electrical stimulus via electrodes applied to the scalp. The original application of ECT in non-anaesthetised patients resulted in many traumatic effects and was replaced, in the early 1960s, with a modified ECT regimen that used anaesthesia with neuromuscular blockade. This remains the worldwide standard today. The development of modern ECT devices, with improved impulse modes, has also reduced the incidence of post-interventional cognitive adverse effects. The variety of centrally-acting co-medications administered and the cardiovascular effects occurring during the procedure make patients receiving ECT a challenge for the anaesthetist. The efficacy of ECT depends on the production of adequate seizures; however, the anaesthetic agents commonly used during ECT suppress the generation of convulsions. Therefore, the efficacy of ECT requires knowledge of anaesthetic precepts, understanding of the interaction between anaesthetic drugs and seizure activity, and awareness of the physiological effects of ECT as well as the treatment of those effects. Successful and safe ECT depends on the correct choice of anaesthetic drugs for the individual patient, which have to be chosen with respect to the individual concomitant medication and pre-existing diseases. This review provides information for the optimal selection, set-up and practice of anaesthetic drug treatment in ECT.

Indexed as

AnestheticsAnimalsElectroconvulsive TherapyHumansPainPsychotic DisordersAnesthetics

Identifiers

PMID16142990
OpenAlexW2013893611

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.