ReviewThe Journal of clinical investigation2005
Mechanisms of sudden cardiac death.
Review in The Journal of clinical investigation, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 184 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
184 citing papers in PubMed, 2 syntheses or guidelines pooled it, 503 citations in OpenAlex.
- Fragmented QRS is associated with ventricular arrhythmias in heart failure patients: A systematic review and meta-analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022Pooled it
- HRS policy statement: clinical cardiac electrophysiology fellowship curriculum: update 2011.Heart rhythm · 2011Guideline
- Sympathetic activity-associated periodic repolarization dynamics predict mortality following myocardial infarction.The Journal of clinical investigation · 2014Trial
- Spinal nociceptive denervation impedes subsequent chronic autonomic remodeling after myocardial infarction in male swine.Nature communications · 2026Article
- Contextual fear conditioning leads to hypo-innervation of the left ventricular myocardium in female but not male C57BL/6J mice.IBRO neuroscience reports · 2026Article
- Adrenergic Hypersensitivity Drives Ventricular Arrhythmias Following Loss of Plexin-Mediated Cardiac Innervation.JACC. Clinical electrophysiology · 2026Article
- Tyrosine Hydroxylase-Expressing Neurons in the Vagal Ganglia: Characterization and Implications.Biomedicines · 2025Article
- CoordinatedeLife · 2025Article
- Traditional and advanced electrocardiographic measures of autonomic function in the population-based KORA-F3 study.European journal of epidemiology · 2025Article
- Ischemia induced repolarization dispersion changes and ventricular arrhythmia: Validation of Frank vectorcardiography parameters: A review.Heart rhythm O2 · 2025Review
- Therapeutic potential of miR-133a-transfected bone marrow mesenchymal stem cell transplantation in improving cardiac function post-myocardial infarction.Journal of cardiothoracic surgery · 2025Article
- Layer-specific proteomic analysis of human hearts in patients with sudden cardiac death.PloS one · 2025Article
- Percutaneous left stellate ganglion block for refractory ventricular tachycardia in structural heart disease: our single-centre experience.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2024Article
- Biomarker Periodic Repolarization Dynamics Indicates Enhanced Risk for Arrhythmias and Sudden Cardiac Death in Myocardial Infarction in Pigs.Journal of the American Heart Association · 2024Article
- Manipulation of Glutamatergic Neuronal Activity in the Primary Motor Cortex Regulates Cardiac Function in Normal and Myocardial Infarction Mice.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Mechanism of Ventricular Tachycardia Occurring in Chronic Myocardial Infarction Scar.Circulation research · 2024Review
- Cardiac arrhythmogenesis: roles of ion channels and their functional modification.Frontiers in physiology · 2024Review
- The Effects of Silymarin on Calcium Chloride-Induced Arrhythmia in Male Rat.Oxidative medicine and cellular longevity · 2024Article
- Possible organ-protective effects of renal denervation: insights from basic studies.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Review
- Plasma Ceramides and Sphingomyelins and Sudden Cardiac Death in the Cardiovascular Health Study.JAMA network open · 2023Article
124 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Despite recent advances in preventing sudden cardiac death (SCD) due to cardiac arrhythmia, its incidence in the population at large has remained unacceptably high. Better understanding of the interaction among various functional, structural, and genetic factors underlying the susceptibility to, and initiation of, fatal arrhythmias is a major goal and will provide new tools for the prediction, prevention, and therapy of SCD. Here, we review the role of aberrant intracellular Ca handling, ionic imbalances associated with acute myocardial ischemia, neurohumoral changes, and genetic predisposition in the pathogenesis of SCD due to cardiac arrhythmia. Therapeutic measures to prevent SCD are also discussed.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.