ReviewCancer gene therapy2006
Genetic strategies for brain tumor therapy.
Review in Cancer gene therapy, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Mesenchymal stem cell-mediated delivery of therapeutic adenoviral vectors to prostate cancer.Stem cell research & therapy · 2019Article
- Exploiting tumor-intrinsic signals to induce mesenchymal stem cell-mediated suicide gene therapy to fight malignant glioma.Stem cell research & therapy · 2019Article
- Tumoricidal effect of human olfactory ensheathing cell mediated suicide gene therapy in human glioblastoma cells.Molecular biology reports · 2018Article
- A New Approach in Gene Therapy of Glioblastoma Multiforme: Human Olfactory Ensheathing Cells as a Novel Carrier for Suicide Gene Delivery.Molecular neurobiology · 2016Article
- Use of genetically engineered stem cells for glioma therapy.Oncology letters · 2016Article
- Tomato thymidine kinase-based suicide gene therapy for malignant glioma--an alternative for Herpes Simplex virus-1 thymidine kinase.Cancer gene therapy · 2015Article
- Brain tumors: Special characters for research and banking.Advanced biomedical research · 2015Review
- Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma.Stem cells translational medicine · 2014Article
- Improved therapeutic effect on malignant glioma with adenoviral suicide gene therapy combined with temozolomide.Gene therapy · 2013Article
- Suppression of STIM1 inhibits human glioblastoma cell proliferation and induces G0/G1 phase arrest.Journal of experimental & clinical cancer research : CR · 2013Article
- Specific inhibition of SRC kinase impairs malignant glioma growth in vitro and in vivo.Molecular therapy. Nucleic acids · 2012Article
- miRNA-mediated immune regulation and immunotherapeutic potential in glioblastoma.Clinical investigation · 2011Article
- Potential role of miRNAs and their inhibitors in glioma treatment.Expert review of anticancer therapy · 2010Article
- Gene therapy and virotherapy: novel therapeutic approaches for brain tumors.Discovery medicine · 2010Review
- Plant thymidine kinase 1: a novel efficient suicide gene for malignant glioma therapy.Neuro-oncology · 2010Article
- Gene therapy as an adjuvant treatment for malignant gliomas: from bench to bedside.Journal of neuro-oncology · 2009Review
- Emerging functions of microRNAs in glioblastoma.Journal of neuro-oncology · 2009Review
- In vivo gene delivery by embryonic-stem-cell-derived astrocytes for malignant gliomas.Neuro-oncology · 2009Article
- Design and application of oncolytic HSV vectors for glioblastoma therapy.Expert review of neurotherapeutics · 2009Review
- Development of recombinant adeno-associated virus and adenovirus cocktail system for efficient hTERTC27 polypeptide-mediated cancer gene therapy.Cancer gene therapy · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gene therapy is a potentially useful approach in the treatment of human brain tumors, which are notoriously refractory to conventional approaches. Most human clinical trials to date have been unsuccessful in terms of improving patient outcome. Recent improvements in viral vectors, the development of stem cell technology, and increased understanding of the mechanism of action of therapeutic transgenes provide hope that the next generation of gene therapeutics may show increased efficacy in treatment of this devastating disease.
Indexed as
Identifiers
16138122What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.