Evidence map›Paper›PMID 16137384›Full record

ReviewCritical care (London, England)2005

Equipment review: the success of early goal-directed therapy for septic shock prompts evaluation of current approaches for monitoring the adequacy of resuscitation.

Scott R Gunn, Mitchell P Fink, Benjamin Wallace

Registry-linked trialAbstract readComparative StudyReview
In one paragraph

Review in Critical care (London, England), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00535821 (A Multi-center Randomized Comparison of a Minimally-invasive Cardiovascular Hemodynamic Optimization), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00535821 phase4terminatednot on this mapstarted 2007, after this paper: background citation

A Multi-center Randomized Comparison of a Minimally-invasive Cardiovascular Hemodynamic Optimization (MiCHO) Protocol Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock Patients Presenting to the Emergency Department

TypeinterventionalSponsorLoma Linda UniversityRan2007 to 2010Enrolled5ConditionsSevere Sepsis, Septic ShockArmsEsophageal Doppler monitoring - CardioQ, Deltex Inc, Central line with CVP and continuous ScvO2 monitoring
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Choosing patient-tailored hemodynamic monitoring.Critical care (London, England) · 2010
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Scott R GunnDepartment of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
Mitchell P Fink
Benjamin Wallace

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A recent trial utilizing central venous oxygen saturation (SCVO2) as a resuscitation marker in patients with sepsis has resulted in its inclusion in the Surviving Sepsis Campaign guidelines. We review the evidence behind SCVO2 and its relationship to previous trials of goal-directed therapy. We compare SCVO2 to other tools for assessing the adequacy of resuscitation including physical examination, biochemical markers, pulmonary artery catheterization, esophageal Doppler, pulse contour analysis, echocardiography, pulse pressure variation, and tissue capnometry. It is unlikely that any single technology can improve outcome if isolated from an organized pattern of early recognition, algorithmic resuscitation, and frequent reassessment. This article includes a response to the journal's Health Technology Assessment questionnaire by the manufacturer of the SCVO2 catheter.

Indexed as

Clinical ProtocolsBiomarkersCatheterization, Central VenousEvidence-Based MedicineHumansOutcome and Process Assessment, Health CareOxygenPredictive Value of TestsResuscitationShock, SepticTreatment OutcomeBiomarkersOxygen

Identifiers

PMID16137384
PMCPMC1269450

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.