ArticleWorld journal of surgery2005
Surgical treatment of appendiceal adenocarcinoid (goblet cell carcinoid).
Article in World journal of surgery, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Guideline
- The Optimal Approach to Surgical Management of Goblet Cell Carcinoid of the Appendix: A Systematic Review.Diagnostics (Basel, Switzerland) · 2024Review
- Right Hemicolectomy and Appendicectomy as Treatments for Goblet Cell Adenocarcinoma: A Comparative Analysis of Two Large National Databases.Current oncology (Toronto, Ont.) · 2024Article
- Role of colectomy in the management of appendiceal tumors: a retrospective cohort study.BMC gastroenterology · 2023Article
- Appendiceal Goblet Cell Carcinoma: Role of Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC).Indian journal of surgical oncology · 2023Review
- Incidental discovery of goblet cell carcinoid, a rare appendiceal malignancy case report.Journal of surgical case reports · 2022Article
- Goblet Cell Adenocarcinoma of the Appendix: A Systematic Review and Incidence and Survival of 1,225 Cases From an English Cancer Registry.Frontiers in oncology · 2022Article
- Omission of Right Hemicolectomy May be Safe for Some Appendiceal Goblet Cell Adenocarcinomas: A Survival Analysis of the National Cancer Database.Annals of surgical oncology · 2021Article
- Article
- Clinicopathological and Perioperative Outcome of Appendiceal Tumors: Case Review of 31 Patients.Spartan medical research journal · 2020Article
- Treatment patterns and outcomes in goblet cell carcinoid tumors of the appendix.Journal of surgical oncology · 2019Article
- ΔNp73 status in peritoneal and ovarian dissemination of appendicular adenocarcinoids (goblet cells).Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2019Article
- Goblet cell carcinoid of the appendix - diagnostic challenges and treatment updates: a case report and review of the literature.Journal of medical case reports · 2018Review
- Goblet cell carcinomas of the appendix: rare but aggressive neoplasms with challenging management.Endocrine connections · 2018Article
- Goblet cell carcinoids of the appendix: Tumor biology, mutations and management strategies.World journal of gastrointestinal surgery · 2016Review
- Appendiceal mixed adenoneuroendocrine carcinomas, a rare entity that can present as a Krukenberg tumor: case report and review of the literature.World journal of surgical oncology · 2015Review
- Article
- Goblet cell carcinoids of the appendix.TheScientificWorldJournal · 2013Review
- [Surgical strategies for accidental detection of appendix carcinoids].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2011Review
- Unusual histopathological findings in appendectomy specimens: a retrospective analysis and literature review.World journal of gastroenterology · 2011Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Adenocarcinoid of the appendix is an infrequent tumor with histologic features of both adenocarcinoma and carcinoid tumor. Although its malignant potential remains unclear, adenocarcinoids seem to be biologically more aggressive than conventional carcinoids. The aim of this study was to analyze long-term results of surgical treatment for appendiceal adenocarcinoid. A retrospective review (1991-2003) identified seven patients (median age 72, range 27-81 years) treated for appendiceal adenocarcinoid. The clinical data of these patients were reviewed. Follow-up was complete for all patients (median 60 months, range 24-108 months). Most cases presented with associated acute appendicitis (71%). First intention surgery consisted of appendectomy (m = 6) and right hemicolectomy (m = 1). In three patients, additional surgical procedures were performed (right colectomy). Indications for colectomy were tumor size (three cases) associated with appendectomy margin invasion in one case. One patient with lymph node and peritoneal involvement experienced recurrence 9 months after hemicolectomy and died of the disease at 2 years. One patient subsequently died of colon carcinoma 6 years after adenocarcinoid treatment. Five patients were alive without disease at the time of the last follow-up. Synchronous or metachronous colon carcinomas developed in three patients (43%). Our results suggest that appendectomy alone could be used for appendiceal adenocarcinoid provided that the tumor (1) is less than 1 cm; (2) does not extend beyond the appendix adventitia; (3) has less than 2 mitoses/10 high power fields; and (4) has surgical margins that are tumor free. Otherwise, carcinologic right colectomy seems to be indicated. The risk for developing colorectal adenocarcinoma seems to be extremely high in patients treated for appendiceal adenocarcinoid and warrants close follow-up with colonoscopic screening.
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