Evidence map›Paper›PMID 16136206›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2005

CAM and cell fate targeting: molecular and energetic insights into cell growth and differentiation.

Carlo Ventura

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Acupuncture May Stimulate Anticancer Immunity via Activation of Natural Killer Cells.Evidence-based complementary and alternative medicine : eCAM · 2011
    Article
  4. eCAM: Integrative Genomics and Fecundity.Evidence-based complementary and alternative medicine : eCAM · 2009
    Article
  5. Immunomodulating Activity of Agaricus brasiliensis KA21 in Mice and in Human Volunteers.Evidence-based complementary and alternative medicine : eCAM · 2008
    Article
  6. Article
  7. Use of magnetic nanoparticles to visualize threadlike structures inside lymphatic vessels of rats.Evidence-based complementary and alternative medicine : eCAM · 2007
    Article
  8. DNA microarrays in herbal drug research.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  9. eCAM: On To Year 4.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  10. Article
  11. Regional Strength in CAM.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  12. Stem cells and CAM.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  13. Evaluation of medicinal plant hepatotoxicity in co-cultures of hepatocytes and monocytes.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  14. Regulatory T cells, a potent immunoregulatory target for CAM researchers: the ultimate antagonist (I).Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  15. Immunology and homeopathy. 2. Cells of the immune system and inflammation.Evidence-based complementary and alternative medicine : eCAM · 2006
    Article
  16. ECAM is waiting for eCAM.Evidence-based complementary and alternative medicine : eCAM · 2005
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Carlo VenturaLaboratory of Molecular Biology and Stem Cell Engineering, National Institute of Biostructures and Biosystems and Institute of Cardiology, S. Orsola-Malpighi Hospital, University of Bologna 40138 Bologna, Italy. carlo.ventura@unibo.it
MRC Laboratory of Molecular Biology · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence-based medicine is switching from the analysis of single diseases at a time toward an integrated assessment of a diseased person. Complementary and alternative medicine (CAM) offers multiple holistic approaches, including osteopathy, homeopathy, chiropractic, acupuncture, herbal and energy medicine and meditation, all potentially impacting on major human diseases. It is now becoming evident that acupuncture can modify the expression of different endorphin genes and the expression of genes encoding for crucial transcription factors in cellular homeostasis. Extremely low frequency magnetic fields have been found to prime the commitment to a myocardial lineage in mouse embryonic stem cells, suggesting that magnetic energy may direct stem cell differentiation into specific cellular phenotypes without the aid of gene transfer technologies. This finding may pave the way to novel approaches in tissue engineering and regeneration. Different ginseng extracts have been shown to modulate growth and differentiation in pluripotent cells and to exert wound-healing and antitumor effects through opposing activities on the vascular system, prompting the hypothesis that ancient compounds may be the target for new logics in cell therapy. These observations and the subtle entanglement among different CAM systems suggest that CAM modalities may deeply affect both the signaling and transcriptional level of cellular homeostasis. Such a perception holds promises for a new era in CAM, prompting reproducible documentation of biological responses to CAM-related strategies and compounds. To this end, functional genomics and proteomics and the comprehension of the cell signaling networks may substantially contribute to the development of a molecular evidence-based CAM.

Identifiers

PMID16136206
PMCPMC1193541
OpenAlexW2114729773

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.