Evidence map›Paper›PMID 16133660›Full record

ArticleJournal of human genetics2005

Microsatellite data support subpopulation structuring among Basques.

Ana M Pérez-Miranda, Miguel A Alfonso-Sánchez, Arif Kalantar, Susana García-Obregón, Marian M de Pancorbo, José A Peña, Rene J Herrera

Open access · bronzeAbstract read
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In one paragraph

Article in Journal of human genetics, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Ana M Pérez-MirandaMolecular Biology and Human Diversity Laboratory, Department of Biological Sciences, Florida International University, Miami, FL, 33199, USA.
Miguel A Alfonso-SánchezDpto de Genética y Antropología Física, Universidad del País Vasco, Apartado 644, Vizcaya, 48080, Bilbao, Spain.
Arif KalantarMolecular Biology and Human Diversity Laboratory, Department of Biological Sciences, Florida International University, Miami, FL, 33199, USA.
Susana García-ObregónDpto de Genética y Antropología Física, Universidad del País Vasco, Apartado 644, Vizcaya, 48080, Bilbao, Spain.
Marian M de PancorboDpto de Zoología y Dinámica Celular Animal, Facultad de Farmacia, Universidad del País Vasco, Vizcaya, 48940, Leioa, Spain.
José A PeñaDpto de Genética y Antropología Física, Universidad del País Vasco, Apartado 644, Vizcaya, 48080, Bilbao, Spain.
Rene J HerreraMolecular Biology and Human Diversity Laboratory, Department of Biological Sciences, Florida International University, Miami, FL, 33199, USA. herrerar@fiu.edu.
University of the Basque Country · ESFlorida International University · USPolice Department · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomic diversity based on 13 short tandem repeat (STR) loci (D3S1358, vWA, FGA, D8S1179, D21S11, D18S51, D5S818, D13S317, D7S820, D16S539, TH01, TPOX, and CSF1PO) is reported for the first time in Basques from the provinces of Guipúzcoa and Navarre (Spain). STR data from previous studies on Basques from Alava and Vizcaya provinces were also examined using hierarchal analysis of molecular variance (AMOVA) and genetic admixture estimations to ascertain whether the Basques are genetically heterogeneous. To assess the genetic position of Basques in a broader geographic context, we conducted phylogenetic analyses based on F(ST) genetic distances [neighbor-joining trees and multidimensional scaling (MDS)] using data compiled in previous publications. The genetic profile of the Basque groups revealed distinctive regional partitioning of short tandem repeat (STR) diversity. Consistent with the above, native Basques clearly segregated from other populations from Europe (including Spain), North Africa, and the Middle East. The main line of genetic discontinuity inferred from the spatial variability of the microsatellite diversity in Basques significantly overlapped the geographic distribution of the Basque language. The genetic heterogeneity among native Basque groups correlates with the peculiar geography of peopling and marital structure in rural Basque zones and with language boundaries resulting from the uneven impact of Romance languages in the different Basque territories.

Indexed as

Genetics, PopulationDNAGene FrequencyGenetic HeterogeneityGeographyHumansLanguageMicrosatellite RepeatsPhylogenyPolymerase Chain ReactionSpainDNA

Identifiers

PMID16133660
OpenAlexW2024314547

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.