Evidence map›Paper›PMID 16132815›Full record

ReviewChromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology2005

Human subtelomere structure and variation.

H Riethman, A Ambrosini, S Paul

2 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 61 papers.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04577560 naunknown statusnot on this mapstarted 2021, after this paper: background citation

Does the Telomere Length in First Human Polar Body Correlates With the Telomere Length in Cumulus Cells: A Clinical Validation Study

TypeinterventionalSponsorART Fertility Clinics LLCRan2021 to 2022Enrolled10ConditionsTelomere LengthArmsFirst polar body biopsy in MII oocytes, PGT-A blastocyst
NCT06732843 recruitingnot on this mapstarted 2025, after this paper: background citation

Does Recombinant FSH (rFSH, i.g. Gonal F®) as Compared to Human Menopausal Gonadotrophin (hMG) Affect Telomere Length of Cumulus Cells During Antral Follicle Growth and Impact Blastocyst Status?

Typeobservational_patient_registrySponsorART Fertility Clinics LLCRan2025 to 2027Enrolled10ConditionsOVARIAN STIMULATION, Telomere Length, Telomere Length, Mean Leukocyte
3 · Its place in the literature

Who cites it

61 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Sequence, Chromatin and Evolution of Satellite DNA.International journal of molecular sciences · 2021
    Review
  6. Review
  7. Review
  8. Article
  9. Subtelomeric Transcription and its Regulation.Journal of molecular biology · 2020
    Review
  10. Review
  11. Review
  12. TheFrontiers in genetics · 2020
    Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Telomere length and telomerase activity during folliculogenesis in mammals.The Journal of reproduction and development · 2018
    Review
  20. Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

H RiethmanWistar Institute, 3601 Spruce St., Philadelphia, PA 19104, USA. Riethman@wistar.org
A Ambrosini
S Paul

Funding

TUMOR DEVELOPMENT AND PROGRESSION IN HUMAN MELANOCYTESP01CA025874 · NCI · WISTAR INSTITUTE · PI HERLYN, MEENHARD F · 1985 to 2015
$19.0M
PHYSICAL MAPPING OF HUMAN TELOMERIC DNAR01HG000567 · NHGRI · WISTAR INSTITUTE · PI RIETHMAN, HAROLD · 1991 to 2010
$4.1M
NCI NIH HHS CA 25874NHGRI NIH HHS HG00567
6 · The paper itself

Abstract

Work towards completion of the human reference genome sequence has revealed a great deal of complexity and plasticity in human subtelomeric regions. The highly variable subtelomeric repeat regions are filled with recently shuffled genomic segments, many of which contain sequences matching transcripts and transcript fragments; the rapid duplication and combinatorial evolution of these regions has generated an extremely diverse set of subtelomeric alleles in the human species, the complexity and potential significance of which is only beginning to be understood. This review summarizes recent progress in analyzing human subtelomeric sequence assemblies and large-scale variation in human subtelomere regions.

Indexed as

Genome, HumanGenetic VariationHumansInterspersed Repetitive SequencesPhysical Chromosome MappingSequence Analysis, DNATelomere

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.