ArticleRNA (New York, N.Y.)2005
An in vitro RNA editing system from cauliflower mitochondria: editing site recognition parameters can vary in different plant species.
Article in RNA (New York, N.Y.), 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 82 citations in OpenAlex.
- Beyond a PPR-RNA recognition code: Many aspects matter for the multi-targeting properties of RNA editing factor PPR56.PLoS genetics · 2023Article
- A ribonuclease activity linked to DYW1 in vitro is inhibited by RIP/MORF proteins.Scientific reports · 2023Article
- Identification of soybean trans-factors associated with plastid RNA editing sites.Genetics and molecular biology · 2020Article
- Towards a comprehensive picture of C-to-U RNA editing sites in angiosperm mitochondria.Plant molecular biology · 2018Article
- Functional divergence and origin of the DAG-like gene family in plants.Scientific reports · 2017Article
- The Reverse Transcriptase/RNA Maturase Protein MatR Is Required for the Splicing of Various Group II Introns in Brassicaceae Mitochondria.The Plant cell · 2016Article
- An RNA recognition motif-containing protein is required for plastid RNA editing in Arabidopsis and maize.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- Deletions in cox2 mRNA result in loss of splicing and RNA editing and gain of novel RNA editing sites.PloS one · 2013Article
- Two related RNA-editing proteins target the same sites in mitochondria of Arabidopsis thaliana.The Journal of biological chemistry · 2012Article
- Multiple organellar RNA editing factor (MORF) family proteins are required for RNA editing in mitochondria and plastids of plants.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- The pentatricopeptide repeat protein OTP87 is essential for RNA editing of nad7 and atp1 transcripts in Arabidopsis mitochondria.The Journal of biological chemistry · 2011Article
- When you can't trust the DNA: RNA editing changes transcript sequences.Cellular and molecular life sciences : CMLS · 2011Review
- The RNA editing pattern of cox2 mRNA is affected by point mutations in plant mitochondria.PloS one · 2011Article
- Reverse genetic screening identifies five E-class PPR proteins involved in RNA editing in mitochondria of Arabidopsis thaliana.The Journal of biological chemistry · 2010Article
- MEF9, an E-subclass pentatricopeptide repeat protein, is required for an RNA editing event in the nad7 transcript in mitochondria of Arabidopsis.Plant physiology · 2010Article
- AtnMat2, a nuclear-encoded maturase required for splicing of group-II introns in Arabidopsis mitochondria.RNA (New York, N.Y.) · 2009Article
- A study of new Arabidopsis chloroplast RNA editing mutants reveals general features of editing factors and their target sites.The Plant cell · 2009Article
- Multiplex single-base extension typing to identify nuclear genes required for RNA editing in plant organelles.Nucleic acids research · 2009Article
- A DYW domain-containing pentatricopeptide repeat protein is required for RNA editing at multiple sites in mitochondria of Arabidopsis thaliana.The Plant cell · 2009Article
- Multiple specificity recognition motifs enhance plant mitochondrial RNA editing in vitro.The Journal of biological chemistry · 2008Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most of the 400 RNA editing sites in flowering plant mitochondria are found in mRNAs. Consequently, the sequence vicinities of homologous sites are highly conserved between different species and are presumably recognized by likewise conserved trans-factors. To investigate the evolutionary adaptation to sequence variation, we have now analyzed the recognition elements of an editing site with divergent upstream sequences in the two species pea and cauliflower. This variation is tolerated at the site selected, because the upstream cis-elements reach into the 5'-UTR of the mRNA. To compare cis-recognition features in pea and cauliflower mitochondria, we developed a new in vitro RNA editing system for cauliflower. In vitro editing assays with deleted and mutated template RNAs show that the major recognition elements for both species are located within the conserved sequence. In cauliflower, however, the essential upstream nucleotides extend further upstream than they do in pea. In-depth analysis of single-nucleotide mutations reveals critical spacing of the editing site and the specific recognition elements, and shows that the +1 nucleotide identity is important in cauliflower, but not in pea.
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