Evidence map›Paper›PMID 16130895›Full record

ReviewHuman cell2005

Tumor angiogenesis and molecular target therapy in ovarian carcinomas.

Masatsugu Ueda, Yoshito Terai, Koji Kanda, Masanori Kanemura, Mikio Takehara, Hikari Futakuchi, Hiroyuki Yamaguchi, Masayuki Yasuda, Koji Nishiyama, Minoru Ueki

Abstract readReview
PubMed Publisher
In one paragraph

Review in Human cell, 2005. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Masatsugu UedaDepartment of Obstetrics and Gynecology, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka 569-8686, Japan. gyn017@poh.osaka-med.ac.jp
Yoshito Terai
Koji Kanda
Masanori Kanemura
Mikio Takehara
Hikari Futakuchi
Hiroyuki Yamaguchi
Masayuki Yasuda
Koji Nishiyama
Minoru Ueki
Osaka Medical and Pharmaceutical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Growth of solid tumors depends on angiogenesis, the process by which new blood vessels develop from the endothelium of a pre-existing vasculature. Tumors promote angiogenesis by secreting various angiogeneic factors, and newly formed blood vessels induce tumor cell proliferation and invasiveness. Ovarian carcinomas have a poor prognosis, often associated with multifocal intraperitoneal dissemination accompanied by intense neovascularization. The degree of angiogenesis of ovarian carcinomas may directly influence the clinical course of the disease. Although a growing body of evidence indicates that angiogenic intensity may play a prognostic role in gynecological malignancies including ovarian carcinomas, the related biological mechanisms remain to be further elucidated. In this review, we describe current knowledge pertaining to mechanisms and regulation of angiogenesis in ovarian carcinomas with special reference to our recent research results.

Indexed as

Genetic TherapyVascular Endothelial Growth Factor AAngiogenesis Inducing AgentsAngiogenesis InhibitorsAngiogenic ProteinsAnimalsAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBevacizumabCarcinomaCell ProliferationExtracellular Matrix ProteinsFemaleGene Expression Regulation, NeoplasticHumansMatrix Metalloproteinase 2Angiogenesis Inducing AgentsAngiogenesis InhibitorsAngiogenic ProteinsAngiozymeAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedBevacizumabExtracellular Matrix ProteinsMatrix Metalloproteinase 2PeptidesRNA, CatalyticSPON1 protein, humanVascular Endothelial Growth Factor A

Identifiers

PMID16130895
OpenAlexW2132936161

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.