Trial reportDrug and alcohol dependence2006
High prevalence of alcohol use among hepatitis C virus antibody positive injection drug users in three US cities.
Trial report in Drug and alcohol dependence, 2006. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00391482 (Behavioral Intervention Trial to Reduce Transmission Risks and Improve HCV Treatment Access Among HCV-infected Injection Drug Users), which is not on this map. Cited by 38 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Behavioral Intervention Trial to Reduce Transmission Risks and Improve HCV Treatment Access Among HCV-infected Injection Drug Users
Who cites it
38 citing papers in PubMed, 2 syntheses or guidelines pooled it, 88 citations in OpenAlex.
- Meta-analysis of depression and substance use and impairment among intravenous drug users (IDUs).Addiction (Abingdon, England) · 2008Pooled it
- Infectious Diseases Among People Experiencing Homelessness: A Systematic Review of the Literature in the United States and Canada, 2003-2022.Public health reports (Washington, D.C. : 1974)Pooled it
- Predictors and effects of alcohol use on liver function among young HCV-infected injection drug users in a behavioral intervention.Journal of hepatology · 2011Trial
- Effects of a hepatitis C virus educational intervention or a motivational intervention on alcohol use, injection drug use, and sexual risk behaviors among injection drug users.American journal of public health · 2009Trial
- Article
- Evaluation of alcohol use behavior among patients cured through HCV elimination program in Georgia.BMC research notes · 2024Article
- Assessment of Alcohol and Other Substance Use in Patients With Chronic Liver Disease.Clinical liver disease · 2022Review
- Cascade of Hepatitis C Virus Care Among Patients With Substance Use Disorders.American journal of preventive medicine · 2021Article
- The use of all-oral direct-acting antivirals in hepatitis C virus-infected patients with substance use disorders.Journal of managed care & specialty pharmacy · 2021Article
- Assessment of liver disease in patients with chronic hepatitis C and unhealthy alcohol use.World journal of gastroenterology · 2021Review
- Direct-acting antiviral treatment uptake and sustained virological response outcomes are not affected by alcohol use: A CANUHC analysis.Canadian liver journal · 2021Article
- Concurrent Alcohol and Opioid Use Among Harm Reduction Clients.Addictive behaviors · 2020Article
- Overlapping epidemics of alcohol and illicit drug use among HCV-infected persons who inject drugs.Addictive behaviors · 2019Observational
- Integrating Care for Patients With Chronic Liver Disease and Mental Health and Substance Use Disorders.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2018Article
- The prevalence of hepatitis B and C among blood donors at the National Blood Transfusion Center (CNTS) in Burundi.The Pan African medical journal · 2018Article
- Is Moderate Alcohol Consumption Safe for Human Immunodeficiency Virus/Hepatitis C Virus-Coinfected Women?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017Article
- Association between alcohol consumption and injection and sexual risk behaviors among people who inject drugs in rural Puerto Rico.Journal of substance abuse treatment · 2017Article
- Alcohol use disorder and its impact on chronic hepatitis C virus and human immunodeficiency virus infections.World journal of hepatology · 2016Review
- Daily alcohol use as an independent risk factor for HIV seroconversion among people who inject drugs.Addiction (Abingdon, England) · 2016Article
- HIV, Hepatitis C, and Abstinence from Alcohol Among Injection and Non-injection Drug Users.AIDS and behavior · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
Injection drug users (IDUs) acquire the majority of new hepatitis C virus (HCV) infections and frequently use alcohol. Alcohol abuse accelerates liver disease among HCV-infected persons, can reduce the effectiveness of treatment for HCV infection and may be a contraindication for HCV treatment. HCV seropositive, HIV-negative IDUs aged 18-35 years in Baltimore, New York City and Seattle who were enrolled in a behavioral risk-reduction intervention trial underwent computerized self-interviews to assess baseline alcohol use and dependence and medical history. We measured problem alcohol use using the 10-item Alcohol Use Disorders Identification Test (AUDIT) scale. Of 598 participants, 84% responded "false" to: "it is safe for a person with HCV to drink alcohol". Problem drinking, defined as score > or =8 on AUDIT, was identified in 37%. Correlates of scoring > or =8 on AUDIT included homelessness, male gender, primarily injecting speedballs, having injected with used needles, prior alcohol treatment and depression. Although most HCV seropositive IDUs in our sample appear informed about their increased risk of liver disease from alcohol, two-fifths screened positive for problem alcohol use. These findings underscore the importance of referring HCV-positive persons to effective alcohol treatment programs to reduce future liver damage and improve eligibility for and effectiveness of treatment of HCV.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.